AIM To assess the association among social status, prevalence of consanguineous marriages, and the effects of consanguinity on reproductive behavior and mortality in Tunisia. METHODS The study included data on a total of 1741 live-births born from November 1989 to October 1990 in the maternity ward of the University-Hospital Fattouma Bourguiba of Monastir, Tunisia. After delivery, women fille...

BACKGROUND AND AIM: Consanguineous marriage is one of the causes of congenital deformities and genetic diseases. The aim of this study was to evaluate the role of consanguineous marriage in dentoalveolar deformities in 16-18 years old adolescents with parental consanguineous marriages in Kerman, Iran. METHODS: A total of 388 female and male adolescents participated in this study. The subjects w...

Meckel Gruber syndrome is an uncommon, lethal, autosomal recessive disorder, associated consistently with polycystic kidneys, posterior encephalocoele and polydactly. We report three cases in non-consanguineous marriages, suggesting that the single gene defect occurs more commonly in non-consanguineous marriages than mutant genes associated with other autosomal recessive disorders that are usua...

OBJECTIVES Consanguinity has been a long standing social habit among some Iranians. This study is aimed at determining the role of consanguinity on congenital malformations and the correlation of inbreeding coefficient with anomalies. METHODS In this cross-sectional study, all the newborns who were born during 9 months period from April to December 2008. (n=1195) at Shahid Sadoughi hospital, ...

background: amelogenesis imperfecta (ai) is an inherited tooth disorder. despite the fact that up to now, several gene muta­tions in mmp20, enam, amelx and klk4 genes have been reported to be associated with ai, many other genes sug­gested to be involved. the main objective of this study was to find the mutations in three major candidate genes including mmp20, enam and klk4 responsible for ai f...

introduction: congenital anomalies are a common cause of disability and mortality in newborns and their treatments involves high costs for the society. this study aimed to investigate the prevalence of congenital anomalies and their causes. materials and methods: this research was a descriptive-analytical study and the population included all the newborns in hospitals of the city of ilam in 201...

Using data on 9762 women from the 1997 Yemen Demographic and Maternal and Child Health Survey, this paper examines the prevalence and socioeconomic correlates of consanguineous marriages in Yemen. The results indicate that 40% of marriages are consanguineous, over 85% of which are between first cousins. The prevalence of consanguineous marriages appears to have increased over time, particularly...

Although the recent Pakistan Demographic and Health Survey (DHS) show that two-thirds of marriages in Pakistan are consanguineous, the sociocultural determinants of such marriages remain largely unexplored. This paper examines the relative importance of the three commonly perceived reasons for such marriages: religious, economic and cultural. The analysis is based on qualitative data collected ...

The effects of consanguineous marriages on couples' fertility and sterility were explored through an interview survey of 20 626 women, chosen randomly from the rural and urban areas of the North Arcot District of Tamil Nadu State. Qualified women investigators obtained relevant information about reproductive performances of all married women resident in well defined rural and urban samples chos...