The modified out-in fuel management strategy was applied to the core loading design for the first four cycles of the Bushehr (Iran-1) KWU designed Pressurized Water Reactor (PWR). The minimum peak-to-average power density was chosen as the objective function of the optimization process. Lattice homogenization and group constants generation were performed by using the LEOPARD computer code. For ...

The compressibility factor of nonassociated chain molecules composed of hard convex core Yukawa segments was derived with SAFT-VR and an extension of the Barker-Henderson perturbation theory for convex bodies. The temperature-dependent chain and dispersion compressibility factors were derived using the Yukawa potential. The effects of temperature, packing fraction, and segment number on the com...

Nucleosome unwrapping dynamics provide transient access to the complexes involved in DNA transcription, repair and replication, while regulation of nucleosome unwrapping modulates occupancy of these complexes. Histone H3 is phosphorylated at Tyrosine 41 (H3Y41ph) and Threonine 45 (H3T45ph). H3Y41ph is implicated in regulating transcription, while H3T45ph is involved in DNA replication and apopt...

conclusions core-lds interaction may be an underlying molecular mechanism to induce liver steatosis in patients with hcv infection. this interaction is also crucial for efficient viral replication and persistence in infected cells. steatosis can also interfere with efficient standard interferon therapy treatment. management of steatosis should be considered along with standard care for achievin...

The apical transmembrane glycoprotein MUC1 is endocytosed to recycle through the trans-Golgi network (TGN) or Golgi complex to the plasma membrane. We followed the hypothesis that not only the known follow-up sialylation of MUC1 in the TGN is associated with this process, but also a remodeling of O-glycan core structures, which would explain the previously described differential core 2- vs core...