Systematic reviews can often reveal much more than the original objective of the work. The objectives of this retrospective analysis were to answer three basic questions about blood pressure variability: 1) Does blood pressure entry criterion have an effect on baseline blood pressure variability? 2) Do thiazide diuretics have a significant effect on blood pressure variability? and 3) Does systo...

I investigated the relation of the maximum rate of left ventricular pressure rise to the end-diastolic volume and the comparison of the maximum rate of left ventricular pressure rise-end-diastolic volume relation to the end-systolic pressure-volume relation, using the time-varying elastance model. These studies were performed in 11 dogs chronically instrumented to measure left ventricular press...

• The normal left ventricular response to progressive proximal aortic obstruction has three phases: (1) a phase of complete compensation in which, following transitory elevations of end-diastolic ventricular pressure (EDVT) and end-diastolic ventricular volume (EDVV), the peak ventricular pressure (PVP) is increased and cardiac output is maintained though end-diastolic ventricular pressure and ...

Although the pericardium can exert a restraining effect on filling of the normal left ventricle, it is uncertain to what extent the pericardium influences left ventricular filling during chronic volume overload. We measured left and right ventricular pressure and left ventricular segment dimension before and after pericardiectomy over a range of left ventricular end-diastolic pressure from <5 t...

Although the pericardium can exert a restraining effect on filling of the normal left ventricle, it is uncertain to what extent the pericardium influences left ventricular filling during chronic volume overload. We measured left and right ventricular pressure and left ventricular segment dimension before and after pericardiectomy over a range of left ventricular end-diastolic pressure from <5 t...

Isovolumic relaxation abnormalities have been noted in the ischemic left ventricle, but altered end-diastolic distensibility, as well as the role of right ventricular distention, is debated. Accordingly, left ventricular end-diastolic pressure and myocardial segment length were studied in the open-chest dogs with critical (90% diameter reduction) stenoses on both left anterior descending and ci...