نتایج جستجو برای: differentiated thyroid carcinoma dtc
تعداد نتایج: 502427 فیلتر نتایج به سال:
Thyroid cancer (TC) is a broad classification of neoplasms that includes differentiated thyroid (DTC) as common histological subtype. DTC characterized by an increased mortality rate in advanced stages, which contributes to the overall high DTC. This progression mainly attributed alterations molecular driver genes, resulting changes phenotypes such invasion, metastasis and dedifferentiation. Cl...
We evaluated the preoperative serum thyrotropin (TSH) levels in 386 patients operated on for nodular thyroid disease (NTD). TSH levels for cases with final benign disease and differentiated thyroid carcinoma (DTC) were compared. No evidence of cancer was detected in 310 patients (80.3%), whereas malignancy was present in 76 cases (19.7%). Mean TSH concentration was 1.36 ± 1.62 mU/L in benign pa...
Thyroid cancer is the most common cancer in Korea. Several susceptibility loci of differentiated thyroid cancer (DTC) were identified by previous genome-wide association studies (GWASs) in Europeans only. Here we conducted a GWAS and a replication study in Koreans using a total of 1,085 DTC cases and 8,884 controls, and validated these results using expression quantitative trait loci (eQTL) ana...
Objectives: The incidence of differentiated thyroid cancer (DTC) has been increasing rapidly in recent years. Patient age at diagnosis is a good prognostic factor for cancer. DTC the only malignancy that includes as part its staging system. American Joint Committee on Cancer (AJCC) system currently uses 55 years cutoff point. In this study, we aimed to compare clinicopathological features patie...
For many years the recommended therapy for differentiated thyroid carcinoma (DTC), with the exception of unifocal papillary carcinoma <1 cm in diameter, has consisted of (near) total thyroidectomy followed by postoperative radioiodine ablation of thyroid remnant tissue. Even though results from randomized controlled trials are still missing, this combination has proven its worth as a safe and v...
Introduction: Retention of I-131 in the body of patients with differentiated thyroid carcinoma (DTC) has a direct effect on therapeutic outcome of radioiodine therapy. There are several factors that may influence retention time of radioiodine in the body of these patients. In this study we are going to assess effects of administered radioiodine activity, serum thyroid stimulati...
OBJECTIVE To analyze the presentation, follow-up and evolution of differentiated thyroid cancer (DTC) detected during pregnancy. SUBJECTS AND METHODS Twenty nine women with DTC detected during pregnancy were analyzed. Group I (n = 13) was seen during pregnancy and DTC was diagnosed during gestation; detection of the nodule occurred during pregnancy (first trimester). Group II (n = 16) was see...
Aggressive histological subtypes of thyroid cancer are rare and have a poor prognosis. The most important aggressive subtypes of thyroid cancer are Hürthle cell carcinoma (HCTC) and anaplastic and poorly differentiated carcinoma (ATC and PDTC). The American Thyroid Association recently published guidelines for the management of patients with ATC, but no specific guidelines have been done about ...
objective(s): in clinical practice, approximately 10-25% of post-surgical differentiated thyroid carcinoma (dtc) patients with high serum thyroglobulin (tg) and negative 131i whole-body scan (wbs) have poor prognosis due to recurrent or metastatic lesions after radioactive iodine treatment. the purpose of this study was to evaluate the value of 18f-fdg pet/ct scan in dtc patients with high seru...
OBJECTIVE The impact of childhood differentiated thyroid carcinoma (DTC) on psychosocial development has not yet been studied. The aim of this study was to evaluate the achievement of psychosocial developmental milestones in long-term survivors of childhood DTC. DESIGN AND METHODS Survivors of childhood DTC diagnosed between 1970 and 2013 were included. Reasons for exclusion were age <18 or >...
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