Realizing the potential of Embryo transfer (ET) for rapid, cheap and widespread dissemination of genetic material, the risk of transmission disease through the embryos must be considered. The aim of this paper is to evaluate theses risks at each step of production, storage and transfer. The pathogen agent may potentially originate from the donor male (semen) or the donor female (oocytes, embryo...

Hepatitis A is one of the most frequent infectious liver diseases affecting children worldwide. The disease is usually mild and self-limited, and complications are very rare. Nevertheless, hepatitis A can sometimes cause acute liver failure (ALF), a severe, life-threatening condition. Herein is reported a case of a child who presented ALF during a course of hepatitis A. The need for early ident...

ABBREVIATIONS IN THIS CHAPTER Anti-Mn Anti-mannan antibody AST Antifungal susceptibility testing ECIL European Conference on Infections in Leukemia ESCMID European Society of Clinical Microbiology and Infectious Diseases IA Invasive aspergillosis IC Invasive candidiasis IDSA Infectious Disease Society of America IFI Invasive fungal infection Mn Mannan antigen TDM Therapeutic drug monitoring 1. ...

Due to its primary fixation purpose antibiotic loaded bone cement (ALBC) has been classified as a class III medical device according to the CE standard for the fixation of primary or revision implants. Because of the high initial release of local antibiotics into the joint cavity, ALBC has also been successfully used for decades for prophylactic reasons aimed at prevention of bacterial colonisa...

Sustained ventricular tachycardia and ventricular fibrillation are life-threatening arrhythmias with high rates of recurrence.1'2 Empiric antiarrhythmic drug therapy has a low success rate for preventing recurrences of these arrhythmias.3 Therefore, the choice of drug therapy has centered around two methodologies to predict drug efficacy: programmed ventricular stimulation with serial drug test...

Sustained ventricular tachycardia and ventricular fibrillation are life-threatening arrhythmias with high rates of recurrence.1'2 Empiric antiarrhythmic drug therapy has a low success rate for preventing recurrences of these arrhythmias.3 Therefore, the choice of drug therapy has centered around two methodologies to predict drug efficacy: programmed ventricular stimulation with serial drug test...

Invasive fungal infections (IFIs) require rapid diagnosis and treatment. A decision-analytic model was used to estimate total costs and survival associated with a diagnostic-driven (DD) or an empiric treatment approach in neutropenic patients with hematological malignancies receiving chemotherapy or autologous/allogeneic stem cell transplants in Shanghai, Beijing, Chengdu, and Guangzhou, the Pe...

BACKGROUND Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. OBJECTIVE To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany. PATIENTS AND METHODS The research reported here was a prospective multicenter longitudinal observational study in adult intensive care unit patients ...