Lyme disease (tick-borne borreliosis, borreliosis - LB) is a multisystem zoonotic transmitted by the bite of infected ticks. Purpose to develop mathematical model for predicting risk severity course (PRSC) LB factor development disseminated in children who have had tick attack. Materials and methods. To build PRSC using multivariate regression analysis, 121 with aged 13±3 years (from 1 18 years...

Objective: The reverse transcription–polymerase chain reaction test (RT-PCR) is the gold standard for diagnosis of coronavirus
 disease 2019 (COVID-19), and antibody tests are useful as supplemental tools diagnosis, measuring population’s immunity
 levels, checking infection in asymptomatic contacts. This study aimed to evaluate reliability five commercial antibody
 detection kit...

A previously healthy 39 year old man was admitted to our hospital with subacute pain and blurred vision in the right eye, in the absence of fever. Physical exam was notable for mydriasis and relative afferent pupillary defect of the right pupil. Visual acuity was 0.5 in the right eye and 1.0 in the left eye. Funduscopic examination of the right eye revealed mild papilledema without concurrent r...

BACKGROUND Voltage-gated potassium channels are thought to be the target of antibodies associated with limbic encephalitis. However, antibody testing using cells expressing voltage-gated potassium channels is negative; hence, we aimed to identify the real autoantigen associated with limbic encephalitis. METHODS We analysed sera and CSF of 57 patients with limbic encephalitis and antibodies at...

Case report. A 47-year-old Tongan male returning to New Zealand after a 2-week holiday in Tonga presented with 3 days of progressive limb weakness, numbness, unsteady gait, and dyspnea. Two days before departing Tonga (6 days before neurologic symptoms), he developed leg swelling with erythematous and pustular lesions, which were treated with flucloxacillin. He had no medical history, was not t...

Background: The clinical significance of pANCA by indirect immunofluorescence is well-established. However, their utility sometimes hindered the fact that are also detected in various autoimmune diseases. Myeloperoxidase (MPO) considered as major autoantigen recognized ANCA-associated vasculitides (AAV) and predominantly microscopic polyangiitis (MPA). information regarding targets other diseas...

Abstract Background Cytomegalovirus (CMV) causes significant morbidity in solid organ transplant recipients (SOTR). As a lack of immunity predisposes to infection, laboratory test that measures CMV-specific cell-mediated (CMV CMI) may help guide antiviral prophylaxis, predict relapses and correlate with outcomes. We assessed CMV CMI D+/R- patients during valganciclovir primary prophylaxis virem...

Abstract Background and Aims We aimed to compare the dynamics of humoral cellular immunity caused by natural COVID-19 or vaccination against SARS-CoV-2 with Gam-COVID-Vac (Sputnik V) vaccine in patients, receiving maintenance hemodialysis (HD). Method Data were extracted from two prospective cohort studies which had investigated long-term immune responses after infection (NCT 04633915) 04805632...