CONTEXT Maternal hypothyroidism and hyperthyroidism have deleterious effects on the outcome of pregnancy. While the effects of thyroid hormone (TH) deprivation on the fetus, independently from that on the mother, can be studied in infants with congenital hypothyroidism, this is not the case in those with fetal thyrotoxicosis. OBJECTIVE To study the effects of TH excess on fetuses carried by m...

The purpose of the paper is IO develop a method of calculating the aggregate loss distribution for a policy covering excess claims over occurrence limit plus claims arising from the primary losses over an underlying annual aggregate. Usually. when working with losses from more than one source you would determine the aggregate distributions of each component and convolute the result IO get the o...

Retinoids are routinely used in dermatology for various clinical entities including acne vulgaris, rosacea, hypertrophic scars, strie distensae, psoriasis, disorders of dyskeratinization, cancer prevention and other chronic hyperkeratotic disorders. Oral acitretin therapy is effective in the treatment of psoriasis normalizing cellular differentiation and maturation but clinical side-effects are...

In this special issue about biofactors causing cognitive impairment, we present evidence for and discuss two such biofactors. One is excess copper, causing neuronal toxicity. The other is zinc deficiency, causing neuronal damage. We present evidence that Alzheimer's disease (AD) has become an epidemic in developed, but not undeveloped, countries and that the epidemic is a new disease phenomenon...

Achieving adequate coverage with high gain antennas is key to realizing the full promise of the wide bandwidth available at mm/cm bands. We report extensive indoor measurements at 28 GHz, with over 1000 links with and without Line-of-Sight (LOS) using a specialized narrowband channel sounder, capable of reliable measurements up to 171 dB path loss to characterize 90% coverage. Azimuthal power s...

Modeling buildings response to blast and subsequent progressive collapse interested more and more researchers during the past two decades. Due to the threat from extreme loading, efforts have been made to develop methods of structural analysis and design. In this paper, progressive collapse capacity of steel moment frames was first investigated using alternate load path method, then a nonlinear...