The wound healing activity of ethanol extract of Terminalia bellirica Roxb. fruit was evaluated on excision and incision wound model, in albino rats, in the form of an ointment with two concentrations (2 and 4% w/w ointment) of fruit extract in simple ointment base. Both concentrations of the ethanol extract showed significant response in both the wound types tested when compared with the contr...

To rationalize scientifically the traditional claim on use of Wedelia biflora (Linn.) D. C. for the treatment of wounds and infections, the present study was designed to evaluate the antimicrobial and wound healing activity of ethanol extract of leaves of W. biflora. In in vitro assays the test extract was subjected to antimicrobial activity by agar well-diffusion method and minimum inhibitory ...

UNLABELLED Multiple therapeutic approaches of the treatment of pilonidal sinuses have been described in the literature, but there are still controversies and lack of standardization. Vacuum Assisted Closure (VAC) therapy has potential beneficial effect on the wound healing after the sinus resection. THE AIM OF THE STUDY To analyze the results of VAC therapy in the treatment of pilonidal sinus...

The methanol leaf extract of Aspila africana formulated as gels was studied for its potency on experimentally-induced wound in rats. Wounds were inflicted on Wistar rats using excision model. The extract was formulated as hydrogel and xerogel. The wound healing effects of the formulations were compared to that of a standard antibiotic, Cicatrin together with the gel bases. In all cases, there w...

Because of a possible delayed wound healing, critical colonization and infection of wounds present a problem for surgeons, particularly in patients with compromised immune system or in case where the wound is heavy contaminated or poorly perfused. Molndal technique of wound dressing has proven to be effective in prevention of infection. In our study we wanted to describe the benefits of the app...

Complex and recurrent pilonidal sinuses are best treated with surgery. Different surgical modalities as complete excision of the pilonidal sinus leave the wound open or procedures like closing the wound with or without reconstructive flap are widely used. The open procedure is radical but may cause broad excision and prolonged morbidity, while risk of infection and rate of recurrence are higher...

Sulfated polysaccharides have shown promising effects on wound healing processes along with many other biological activities. The sulfated polysaccharides extracted from two algae species habitats in Persian Gulf were studied in vivo for their effects on collagen formation and epidermal regeneration. The polysaccharides were purified from aqueous extracts of P. tetrastromatica and P. boergeseni...

Figure 1. Two-year-old boy with a giant congenital melanocytic nevus of the left buttock. Left, Center, Preoperative views. Right, Immediate view after excision and placement of the Integra bilayer matrix dressing. Figure 2. Left, Wound after removal of the silicone layer of the Integra bilayer matrix dressing. Right, Coverage of the wound with a split skin autograft.

Although burn wound excision and grafting have been shown to improve patient survival, the effects on immune function, especially humoral immunity, are not completely understood. The purpose of this study was to investigate the effect of immediate and early wound excision on antibody synthesis and B-cell proliferation, specifically, antibody response to PGPS, a ubiquitous bacterial cell wall an...

BACKGROUND The elliptical excision is the standard method of removing benign skin lesions, such as congenital melanocytic nevi. This technique allows for primary closure, with little to no dog-ear deformity, but may sacrifice normal tissue adjacent to the lesion, resulting in scars which are unnecessarily long. This study was designed to compare the predicted results of elliptical excision with...