نتایج جستجو برای: experimental autoimmune encephalomyelitis eae
تعداد نتایج: 767110 فیلتر نتایج به سال:
Background and purpose: Using allogeneic and xenogeneic mesenchymal stem cells (MSCs) has had some successful results in the treatment of experimental autoimmune encephalomyelitis (EAE). But the use of its syngeneic counterparts in treatment of EAE, especially established EAE, has had some paradoxical results. This study aimed to evaluate the therapeutic potential of syngeneic bone marrow-deriv...
Abbreviations: CAT, chloroform acetyltransferase; CDR, complementary determining region; EAE, experimental autoimmune encephalomyelitis; GAD65, glutamic acid decarboxylase 65; HEL, hen egg lysozyme; MBP, myelin basic protein; MLN, mesenteric lymph node; NOD, nonobese diabetic; PLN, pancreatic lymph node; scTCR, single-chain TCR; sIA-Ig, soluble IA-Ig; SPR, surface plasmon resonance; TCR, T cell...
multiple sclerosis (ms) is an inflammatory disease of the central nervous system of presumed autoimmune etiology. one of the best animal models of demyelinating diseases is experimental autoimmune encephalomyelitis (eae), which can be induced in a variety of animals by injection of a target antigen such as myelin basic protein (mbp). the immune responses against the target amino acids cause tis...
Results. USPIOs covalently attached to antibodies affected the contrast in MRM scan, and their accumulation on cells manifested as signal weakening in T2*-weighted images or signal enhancement in T1-weighted images. With this method applied in the experimental autoimmune encephalomyelitis (EAE) murine multiple sclerosis (MS) model, CNS-infiltrating CD4 T cells were easily visualized with cell-s...
experimental autoimmune encephalomyelitis (eae) is a mouse model for multiple sclerosis (ms), this autoimmune disease is mainly mediated by adaptive and innate immune responses that lead to an inflammatory demyelination and axonal damage. imatinib mesylate is a selective protein tyrosine kinase inhibitor with immunomodulatory properties that abrogates multiple signal transduction p...
The impact of high-intensity exercise on disease progression and muscle contractile properties in experimental autoimmune encephalomyelitis (EAE) remains unclear. Control (CON) and EAE rats were divided into sedentary and exercise groups. Before onset (experiment 1, n=40) and after hindquarter paralysis (experiment 2, n=40), isokinetic foot extensor strength, cross sectional area (CSA) of tibia...
Objective Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces cell apoptosis by transducing apoptosis signals after interacting with its receptor (TRAIL-R). Although the actual biological role of TRAIL remains to be elucidated, recent accumulating evidence implies that TRAIL regulates immune responses and immune cell homeostasis via an apoptosis-independent pathway, suggesti...
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