Objectives: This study was designed to evaluate the psychometric features of the Persian version of the Fatigue Impact Scale (FIS-P) tool when used in Iranian MS patients. Methods: 140 MS patients and the equivalent number of healthy controls completed the following assessments: FIS-P, Fatigue Severity Scale (FSS), SF-36 questionnaire and  the Mini-Mental State Examination (MMSE). ...

Treatment with acetyl L-carnitine (ALCAR) has been shown to improve fatigue in patients with chronic fatigue syndrome, but there have been no trials on the effect of ALCAR for treating fatigue in multiple sclerosis (MS). To compare the efficacy of ALCAR with that of amantadine, one of the drugs most widely used to treat MS-related fatigue, 36 MS patients presenting fatigue were enrolled in a ra...

PURPOSE/OBJECTIVES To identify differences in fatigue, other physical symptoms, and psychological symptoms and their relationship to quality of life (QOL) during chemotherapy and as long as one year after. DESIGN Longitudinal, descriptive design embedded in a pilot intervention study. SETTING Midwestern urban oncology clinics and patient homes. SAMPLE 25 Caucasian women, aged 40-65 years ...

We evaluated the frequency of fatigue in geriatric patients with and without Parkinson's disease (PD) and correlated it with depression and excessive daytime sleepiness. We evaluated 100 patients from Hospital São Paulo, 50 with PD from the Neurologic Outpatient Clinic and 50 with non-neurologic diseases or oncologic diseases from the Geriatric Outpatient Clinic (controls). All patients who sco...

original article   shift work is a common work schedule that has several inappropriate consequences, the most important of which is fatigue. the aim of this study was to invest gate the impact of the shift length on the occupatio al fatigue of operators in filling stations. this cross-sectional study was carried out on operators of the filling station in national iranian oil products distributi...

BACKGROUND Fatigue is a disabling syndrome in multiple sclerosis (MS), which may be associated with inflammation and faster disease progression. OBJECTIVE To analyze the significance of cognitive fatigue for subsequent disease progression. METHOD We followed 46 MS patients and 14 healthy controls in a study over 17 months. At the beginning (t1) and at the end (t2) of the study participants ...

Fatigue, the enduring sensation of weakness, lack of energy, tiredness or exhaustion, is described by 40%-80% of patients with rheumatoid arthritis as their most disabling symptom with wide-ranging consequences for quality of life. Little attention has been paid to its multidimensional nature or to its reliability as a measure to evaluate progression of the disease. Low impact aerobic exercise ...

BACKGROUND People with multiple sclerosis (MS) often report poor sleep, fatigue, sleepiness, depression and cognitive dysfunction. Interrelationships between symptoms and sleep are poorly understood. OBJECTIVES To document objective parameters of sleep measured by polysomnography (PSG) and multi-sleep latency tests (MSLTs) in patients experiencing fatigue or sleepiness and to determine whethe...