The design of software systems tend to degrade throughout time. Changes in code end up introducing new and unplanned dependencies among modules, causing the elegance of the design to be slowly lost in the form of structural patches and violations of previously established architectural rules. In this study, we propose a conceptual framework for dependency management. Our aim is to conceive a fr...

in the present study, interactions between lead exposure with nitric oxide precursor (l-arginine) or nitric oxide synthase (nos) inhibitor (l-name) on naloxone-induced jumping and diarrhea in morphine-dependent mice were examined. chronic lead acetate (0.05%) exposure altered naloxone-induced jumping and diarrhea in mice. jumping was decreased after 7 days and was unchanged 14 and 28 days after...

We present a new way to tune the electron-phonon coupling (EPC) in graphene by changing the deformation potential with electron/hole doping. We show the EPC for highest optical branch at the high symmetry point K acquires a strong dependency on the doping level due to electron-electron correlation not accounted in mean-field approaches. Such a dependency influences the dispersion (with respect ...

Virtual environment (VE) users often report having a sense of being present in the virtual place or a sense that the virtual object is present in their environment. This sense of presence depends on both the technological fidelity (e.g., in graphics, haptics) and the users' cognitive/ personality characteristics. This study examined the correlation between user's cognitive style on the field-de...

MOTIVATION The advent of high-throughput DNA methylation profiling techniques has enabled the possibility of accurate identification of differentially methylated genes for cancer research. The large number of measured loci facilitates whole genome methylation study, yet posing great challenges for differential methylation detection due to the high variability in tumor samples. RESULTS We have...

The accelerating fields (e. g. centrifugal acceleration and constant acceleration) can change the physical performance of nano-sensors significantly. Herein, a new size-dependent model is developed to investigate the scale-dependent dynamic behavior of nanowire-fabricated sensor operated in an accelerating field. The scale-dependent equation of motion is developed by employing a consolidation o...

Background: The angular dependency of response for TLD cards may cause deviation from its true value on the results of environmental dosimetry, since TLDs may be exposed to radiation at different angles of incidence from the surrounding area.Objective: A 3D setting of TLD cards has been calibrated isotropically in a standard radiation field to evaluate the improvement of the accuracy of meas...

This paper employs one-dimensional numerical ground response analysis models to investigate seismic response of shallow cohesive and non-cohesive soil deposits on vertical propagation of horizontal shear waves. Soil response is modelled by traditional equivalent-linear (EL) frequency-domain analysis using DEEPSOIL software and nonlinear (NL) time-domain analysis using OPENSEES software. The ana...

the purpose of this research was to determine the efficacy of group schema therapy approach for b category personality disorders score adjustment in substance dependent individuals. the present study was performed on individuals under maintenance treatment with methadone in shiraz public centers. sample group included 30 persons who were under treatment. instruments used included: clinical inte...