Background There are over 15 million people with food allergies, 38% of which suffer from more than 1 food allergy. With increasing interest in oral immunotherapy (OIT) as a potential treatment, the safety of ingesting known allergens is a major concern. Little to no data are available for OIT with multiple simultaneous allergens. Also, the effect of omalizumab as adjunctive therapy in rush mul...

Background: The honey bee of the Apis mellifera species is main type cultivated in almost all countries world, including Indonesia. Honey has benefits various aspects, food, health, and beauty. Royal jelly a daily food menu as supplement to maintain increase health vitality. Purpose: Analyzing immunogenic toxinogenic proteins carpatica immunotherapy. Method: Conversion nucleotides into amino ac...

INTRODUCTION Food allergy is an increasing problem with limited therapeutic approaches apart from to the eviction diet. CASE PRESENTATION A 40-year-old female patient with food allergy symptoms was polysensitized to almost all vegetable food since the age of 36; the onset of symptoms was during pregnancy. The allergological study demonstrated positive skin prick tests (SPT) to nuts, legumes, ...

Immunotherapy encourages the recipient's own immune response to destroy cancer cells, and current evidence suggests that immunotherapies may be most beneficial in early metastatic castration-resistant prostate cancer (mCRPC). Sipuleucel-T is the first therapeutic cancer vaccine to be approved by both the US Food and Drug Administration and European Medicines Agency for the treatment of asymptom...

BACKGROUND Thirty percent of children with food allergy are allergic to more than one food. Previous studies on oral immunotherapy (OIT) for food allergy have focused on the administration of a single allergen at the time. This study aimed at evaluating the safety of a modified OIT protocol using multiple foods at one time. METHODS Participants underwent double-blind placebo-controlled food c...

This article reviews the recent advances and current state of equipoise in the use of immunotherapy for IgE-mediated food allergy. It examines the various methods currently under evaluation for induction of desensitisation and tolerance in food allergy and encompasses permissive diets which allow for inclusion of extensively heated food allergens, specific oral tolerance induction (SOTI), the u...

The pioneers of tumor immunology and cancer immunotherapy, including the late William B. Coley and Lloyd J. Old, have championed the potential for immunotherapy for over a century. Finally, advances in our understanding of the fundamentals of tumor immunology are translating into clinical success, with recent US Food and Drug Administration approval of several immunotherapies that improve clini...

Radiotherapy (RT) has been a fundamental component of the anti-cancer armamentarium for over a century. Approximately half of all cancer patients are treated with radiotherapy during their disease course. Over the two past decades, there has been a growing body of preclinical evidence supporting the immunomodulatory effects of radiotherapy, particularly when combined with immunotherapy, but onl...

PURPOSE In 2014, the US Food and Drug Administration approved the first targeted agent, bevacizumab, in the treatment of advanced stage, persistent, or recurrent cervical cancer. This oncologic milestone has catalyzed interest in the investigation of alternate therapies, including immunotherapy, in an effort to extend life and possibly cure patients with advanced stage disease. METHODS This r...