The structure of the racemic title compound, C(10)H(15)NO(4), consists of a tricyclic skeleton comprising a six-membered piperidine ring and five-membered isoxazolidine and tetra-hydro-furan rings. The piperidine ring adopts a distorted chair conformation, while the isoxazolidine and tetra-hydro-furan rings have envelope conformations.

A series of new mannich base derivatives 4-(furan-2-yl(2-(furan-2-yl methylene)hydrazinyl)methyl)morpholine(1-6) were synthesized and synthesized compounds (16) were confirmed by IR, 1H NMR, 13C NMR, Mass spectral, mass spectral fragmentation and elemental analysis. Synthesized compounds (1-6) were screened for antimicrobial activity. Structural activity relationship has been discussed in this ...

In the mol-ecule of the title compound, C(23)H(27)NO(5), the furan ring adopts an envelope conformation. Intra-molecular C-H⋯O inter-actions result in the formation of S(5) and S(6) motifs. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules through C(6) and C(8) chains along the [100] and [010] directions, generating a two-dimensional network.

The title compound, C(20)H(15)Br(2)NO(3), shows the furan ring to adopt a half-chair conformation and the two ring systems to be approximately perpendicular [dihedral angle = 71.0 (2)°]. In the crystal structure, inter-molecular C-H⋯O contacts link the mol-ecules.

In the title compound, C(12)H(13)BrO(2)S, there are two symmetry-independent mol-ecules, A and B, in the asymmetric unit. The crystal studied was an inversion twin with a 0.70 (2):0.30 (2) domain ratio. The methyl-sulfinyl group in mol-ecule B is disordered over two positions with site-occupancy factors fixed at 0.6 and 0.4. The crystal structure is stabilized by C-H⋯O hydrogen bonds and inter-...

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Many benzo[b]furan lignans are known to be biologically active in nature. 2-(3'-Methoxy-4'-hydroxy-phenyl)-5-(3-hydroxypropyl)-7-methoxy-benzo[b]furan-3-carbaldehyde (XH-14) is found as a bioactive component isolated from the plant Salvia miltiorrhiza, commonly known as Danshen, which is a traditional Chinese medicine that is used as a cardiovascular medication. This study examined whether 3 di...

BACKGROUND Evidence of potent rodent carcinogenicity via an unclear mechanism suggests that furan in various foods [leading to an intake of up to 3.5 microg/kg body weight (bw)/day] may present a potential risk to human health. OBJECTIVES We tested the hypothesis that altered expression of genes related to cell cycle control, apoptosis, and DNA damage may contribute to the carcinogenicity of ...

In the title furan-carboxamide derivative, C11H8N2O4, the benzene and furan rings are rotated from the mean plane of the central fragment by 2.68 (5) and 7.03 (4)°, respectively. The nitro group forms a dihedral angle of 10.15 (5)° with the adjacent benzene ring. In the crystal, mol-ecules are linked by weak C-H⋯O inter-actions, forming helical chains running along [010].