In mammalian cells, murine N-methylpurine DNA glycosylase (MPG) removes bases damaged spontaneously or by chemical agents through the process called base excision repair (BER). In this study, we investigated the influence of POL β deficiency on MPG-initiated BER efficiency and the expression levels of BER-related proteins in log-phase and growth-arrested (G(0)) mouse embryonic fibroblasts (MEFs...

Celecoxib inhibits proliferation and induces apoptosis in human tumors, but the molecular mechanisms for these processes are poorly understood. In this study, we evaluated the ability of celecoxib to induce toxicity in head and neck squamous cell carcinomas (HNSCC) and explored the relationships between celecoxib-induced cell cycle inhibition and toxicity in HNSCC. Celecoxib inhibited the proli...

We consider the problem of approximating an M/G/1 queueing system by M/PH/1 system. Namely, unknown general service time distribution G is approximated a phase-type PH. The approximation as well estimation parameters means statistical methods results in perturbations that may affect its performance measures. In this work, we provide strong stability method, mathematical justification method dis...

Attributing the recent CLEO discovery of B → η ′ + X s to originate (primarily) from the fragmentation of an off-shell gluon (g *) via b → s + g * , g * → g + η ′ , we emphasize that many such states (X g) should materialize. Indeed the hadronic fragments (X g) of g * states are closely related to those seen in ψ → γ(φ, ω) + X g. A particular final state of considerable interest is X g = K + K ...

BHT é um antioxidante usado como aditivo em alguns alimentos e em plásticos de embalagens, e sua presença em água mineral engarrafada é possível devido à migração do aditivo contido nas paredes do recipiente. Planejamento fatorial foi empregado para determinar os valores ótimos para os parâmetros operacionais principais na análise de hidroxitolueno butilado (BHT) em água engarrafada usando micr...

background: monitoring of indicator and pathogenic microorganisms is essential for proper composting. the aim of this study was to evaluate the change in population of coliform bacteria and salmonella spp. in composting process of municipal wastes and after its application on soil. methods: the samples were taken from each raw waste pile, initial pile, and active phase pile, cooling phase pile ...