a twelve year old girl, an established case of systemic lupus erythematosus, was referred to us suffering from diplopia and nasal speech for a period of 3 months. neurological examination was conducted which revealed a right-sided sixth nerve palsy and a pulsatile nasopharyngeal mass. neurodiagnostic imaging studies confirmed a giant intracavernous internal carotid aneurysm. the malady of the a...

OBJECTIVE To determine whether patients with condylomata acuminata have an increased risk of developing cancer. DESIGN Prospective cohort study on patients diagnosed as having condylomata acuminata. The number of malignant tumours in the cohort was compared with national incidences obtained from the Swedish Cancer Registry. SETTING Dermatology department of the Karolinska Hospital, Stockhol...

The safety and efficacy of intralesionally administered interferon alfa-2b were assessed in 11 patients suffering from condylomata acuminata for four to 10 months for whom application of podophyllum resin had proved unsuccessful. Three warts from each patient were injected with 10(6) IU interferon alfa-2b three times a week for three weeks. Treatment was followed by a 13 week observation period...

introduction giant fibroadenoma is a rare disease with unknown etiology. during pregnancy, fibroadenomas increase in size and may show lactational histologic changes. high concentrations of estrogen, progesterone, and prolactin promote the ductal growth and formation of tubuloalveolar structures. this may be a reason for the significant enlargement in this period. case presentation we presented...

Giant condyloma acuminatum, also known as Buschke-Löwenstein tumor that occurs in ano-genital region and transmitted by sexual way. Giant condyloma acuminatum is an indolent cauliflower-like tumor, but unlike simple condyloma, it is locally aggressive and destructive. In spite of its histologically benign appearance, it may behave malignantly. We present in this report a 55 years old married ma...

Giant condyloma acuminata are associated with malignant transformation in up to 50% of cases, high recurrence rate, and poor prognosis. Treatment strategies have included wide local excision, abdominopelvic resection, and addition of radiotherapy and adjuvant and/or neoadjuvant systemic chemotherapy.