OBJECTIVE The aims of this study were to evaluate the reproducibility of the Gleason grading system and to compare its interobserver variability with the novel Gleason grade grouping proposal using a large sample volume. MATERIALS AND METHODS In total, 407 pathology slides of prostate needle biopsies from 34 consecutive patients with prostate cancer were re-evaluated. The International Societ...

We consider a generalized version of the sign uncertainty principle for Fourier transform, first proposed by Bourgain, Clozel and Kahane in 2010 revisited Cohn Goncalves 2019. In our setup, signs function its transform resonate with generic given $P$ outside ball. One essentially wants to know if how soon this resonance can happen, when facing suitable competing weighted integral condition. The...

UNLABELLED Study Type - Diagnostic (exploratory cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Due to sampling error, the Gleason score of clinically localized prostate cancer is frequently underestimated at the time of initial biopsy. Given that this may lead to inappropriate surveillance of patients with high-risk disease, there is considerable interest...

OBJECTIVES Prostate cancer Gleason score 6 is the most common score detected on prostatic biopsy. We analyzed the clinical parameters that predict the likelihood of Gleason score upgrading after radical prostatectomy. METHODS The study population consisted of 241 patients who underwent radical retropubic prostatectomy between Feb 2002 and Dec 2007 for Gleason score 6 adenocarcinoma. The influ...

PURPOSE In prostate cancer biopsy Gleason score predicts stage and helps determine active surveillance suitability. Evidence suggests that small incremental differences in the quantitative percent of Gleason pattern 4 on biopsy stratify disease extent, biochemical failure following surgery and eligibility for active surveillance. We explored the overall quantitative percent of Gleason pattern 4...

In this article, we extend the theory of multiplicative chaos for positive definite functions in R of the form f(x) = λ ln T |x| + g(x) where g is a continuous and bounded function. The construction is simpler and more general than the one defined by Kahane in 1985. As main application, we give a rigorous mathematical meaning to the Kolmogorov-Obukhov model of energy dissipation in a turbulent ...

Aleksandrov, Anderson and Nicolau have found examples of inner functions that are in the little Bloch space with a specific rate of convergence to zero. As a corollary they obtain positive singular measures defined in the boundary of the unit disc that are simoultaneously symmetric and Kahane. Nevertheless their construction is very indirect. We give an explicit example of such measures by mean...

Purpose. To determine association between apparent diffusion coefficient value on diffusion-weighted imaging and Gleason score in patients with prostate cancer. Methods. This retrospective case series was conducted at Radiology Department of Aga Khan University between June 2009 and June 2011. 28 patients with biopsy-proven prostate cancer were included who underwent ultrasound guided sextant p...