Many human diseases including development of cancer is associated with depletion of mitochondrial DNA (mtDNA) content. These diseases are collectively described as mitochondrial DNA depletion syndrome (MDS). High similarity between yeast and human mitochondria allows genomic study of the budding yeast to be used to identify human disease genes. In this study, we systematically screened the pre-...

carbon dioxide (co2) concentration of the global atmosphere has increased during the last decades. increasing global atmospheric co2 concentrations are expected to influence crop production. in order to evolution of co2 concentration effects on morphophysiologycal traits in tagets, ageratum and gauilardia, a factorial experiment based on completely randomized design with 3 replications and 12 t...

jeremy shiffman’s editorial appropriately calls on making all forms of power more apparent and accountable, notably productive power derived from expertise and claims to moral authority. this commentary argues that relationships based on productive power can be especially difficult to reveal in global health policy because of embedded notions about the nature of power and politics. yet, it is e...

Due to the complex structural issues and increasing number of design variables, a rather fast optimization algorithm to lead to a global swift convergence history without multiple attempts may be of major concern. Genetic Algorithm (GA) includes random numerical technique that is inspired by nature and is used to solve optimization problems. In this study, a novel GA method based on self-a...

This paper presents an overview of the recent advances in deterministic global optimization approaches and their applications in the areas of Process Design and Control. The focus is on global optimization methods for (a) twice-diierentiable constrained nonlinear optimization problems, (b) mixed-integer nonlinear optimization problems, and (c) locating all solutions of nonlinear systems of equa...

In this contribution we give a brief review of the theory of integer estimation as it has been developed for use with the Global Positioning System (GPS). First we consider the GPS observation equations (GPS and Integers). These observation equations are not of the usual type, since some of the parameters are known to be integer. This implies that an extention of ’classical’ adjustment theory i...