Anthocyanins are thought to have antioxidant effects in the body. The effects of two anthocyanins, malvidin and peonidin, on activity of antioxidant enzymes, glutathione-Stransferase (GST), glutathione reductase (GR), and glutathione peroxidase (GPx), were examined in HT-29 human adenocarcinoma cells. Cells were treated with each anthocyanin or a combination of both at concentrations of 0, 5, a...

BACKGROUND Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The aim of the study was to examine the effects of Optisol-GS and castor oil on lens cond...

Objective: Today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-ZrO2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. However, there are some reports implying that use of nano-ZrO2 is associated with cytotoxic effects like inhibiting the cell proliferation, DNA damage and apoptosis. In the present study, we examined whether nano-Z...

In this work were investigated the physiological and biochemical responses depended on toxic effect caused by different concentrations of herbicides called as 2.4-Dichlorophenoxyacetic acid (2.4-D) herbicide in seedlings that belong to three wheat varieties. The seeds which (Triticum aestivum L. Bayraktar cv., İkizce cv. Tosunbey cv.) used plant material. 15-day old for each variety divided int...

The abilities of cysteine-containing compounds to support growth of Bordetella pertussis and influence pertussis toxin transcription, assembly, and secretion were examined. Cysteine is an essential amino acid for B. pertussis and must be present for protein synthesis and bacterial growth. However, cysteine can be metabolized to sulfate, and high concentrations of sulfate can selectively inhibit...

The antioxidant capacity of the glutathione redox cycle and the concentrations of selenium in serum, red blood cells or whole blood, and polymorphonuclear leucocytes was evaluated in nine patients with severe rheumatoid arthritis (RA) and eight healthy controls receiving daily supplementation with 250 micrograms selenomethionine for six months. Serum and whole blood concentrations of selenium a...

This report shows that glutathione affects ascorbic acid degradation in aqueous solution resulting in a significant stabilization of the vitamin. For the GSH concentrations used in this work the effect was higher on diluted ascorbic acid solutions. It is also shown that for a fixed ascorbic acid concentration, as glutathione concentration increases the degradation reaction shifts from first to ...

It has been reported that glycolysis in mouse brain homogenates is inhibited by ferrous sulfate (1). It was shown that the inhibition is due to an iron-activated factor (IF) in brain and is localized at the stage of triose phosphate oxidation. Later, it was found that glyceraldehyde-3-phosphate dehydrogenase, the triose phosphate-oxidizing enzyme, could be protected by the addition of small amo...