2 Introduction Cochlear microphonic potentials (CM) can be recroded from the intact organ of Corti, but it is still an open question whether they are essential phenomena in the sound reception of hair cells. In order to determine what motivates the release of chemical transmitters at the synaptic end of hair cells, potentials in response to sound stimulations have to be intracellularly recorded...

Background: One of the key questions in biochemistry is why cell becomes aged and what are the involved factors? Why cell growth is stopped after some divisions and cells become senescent? This occurs in a greater frame in the whole body and cells dye after a while. Androgenetic alopecia (AGA) is characterized by a loss or decrease in hair follicle size, which could be related to the loss of ha...

Loss of colour in hair is due to varied reasons like genetic influence, effect of environmental factors, use of alcoholic preparations, etc. Though the permanent synthetic hair dyes are available in different colour ranges and retain natural lustre, they have the chief disadvantage of producing hypersensitive reactions in some individuals. In the present investigation various combinations of po...

Sir, Paraphenylenediamine (PPD), a derivative of paranitroanaline, is commonly used in several industries like oxidizable hair dye, dyeing furs, photochemical processes and tyre vulcanization. The Þ rst documentation of systemic PPD poisoning in 1924 described the case of a hairdresser who developed toxicity from handling the dye.[1] Many reports have followed since then, mainly from developing...

One of the oldest and most well-known cosmetics, hair color has been used by numerous ancient cultures throughout history on both men women. It involves treating with various chemical compounds for changing color. According to how long they remain in hair, these products are primarily divided into two categories: temporary permanent. This classification is consistent types active substances dye...

The molecular composition of the hair cell transduction channel has not been identified. Here we explore the novel hypothesis that hair cell transduction channels include HCN subunits. The HCN family of ion channels includes four members, HCN1-4. They were originally identified as the molecular correlates of the hyperpolarization-activated, cyclic nucleotide gated ion channels that carry curren...

Hair dye ingredients frequently produce positive results in short-term in vitro genotoxicity tests, although results from in vivo assays are typically negative, especially for ingredients in use today. The use of hair dyes is quite widespread resulting in the exposure both for persons working in hairdressing salons and for individuals who have their hair dyed. This provides the opportunity to a...