The acute and sub-acute toxicity of safranal were studied in rat and mice within 2 and 21 days after exposure, respectively. For subacute toxicity, changes in weight as well as biochemical, hematological and pathological parameters were studied. The intraperitoneal LD50 values of safranal were 1.48 mL/kg in male mice, 1.88 mL/kg in female mice and 1.50 mL/kg in male rats. Oral LD50 values were ...

INTRODUCTION Lumpy skin disease (LSD) is an acute viral disease of cattle that is currently emerging in the Middle East region and poses a serious threat to Europe and the rest of the world. The objective of this study was to describe hematological and serum biochemical findings associated with natural clinical infection of LSD in cattle. METHODOLOGY A total of 129 animals clinically infected...

The probiotic activity of Bacillus subtilis was evaluated by its effect on the hematological and biochemical factors of rainbow trout. The experience was carried out in 2 groups (Control and Treatment) and 3 replicates. In Control group, probiotic was not applied in diet but in Treatment group, B. subtilis was administered in feed at a concentration of 10 cells/g. In the day of thirty, 5 blood ...

AIM This study was conducted to evaluate the impact of hot dry, hot humid and comfortable season on physiological, hematological, biochemical, and oxidative stress parameters in Surti buffaloes. MATERIALS AND METHODS Ten lactating Surti buffaloes of similar physiological status were selected. Based on the temperature-humidity index (THI), their natural exposure to the environment was categori...

Jacaranda decurrens subsp. symmetrifoliolata Farias & Proença (Bignoniaceae) is a species traditionally used for the treatment of inflammatory and infectious diseases. Previous findings from our group reported scientifically that J. decurrens has anti-inflammatory efficacy. However, more toxicological studies are needed to support and ensure its safe use. The present study was carried out to ev...

Fifty 1-2-month-old Guinea pigs were divided into 5 equal groups, 10 each. Control (Gp1) did receive neither viable bacteria nor treatment. Each animal from the other groups (Gp2-5) was challenged with (1-2 × 10(8)) viable E. coli in 200  μ L normal saline (0.9%) through IP route. GP2 infected group was treated with 200  μ L saline IP and kept as positive control group. Gp3-4 are infected and t...

An epidemiological cross-sectional study was conducted in Greece to investigate health outcomes associated with long-term exposure to chromium via drinking water. The study population consisted of 304 participants. Socio-demographics, lifestyle, drinking water intake, dietary habits, occupational and medical history data were recorded through a personal interview. Physical examination and a mot...

Purpose: To investigate the effect of vomit seed homeopathic drugs (14CH and 30CH) on paracetamolinduced toxicity in rats.
 Methods: Thirty-two male Wistar rats were divided into 4 groups 8 animals each (n = 8) treated for 12 days. During treatment period, group (G) one (G1) which constitutes control received filtered water, whereas two (G2), three (G3), four (G4) gavaged with a toxic dose...

abstract the present study was carried out to investigate the efficacy of two anesthetics, clove oil and ketamine, comparison of hematological parameters, and blood biochemical indices under optimum doses of the two anesthetics in juvenile sterlet acipenser ruthenus (n=276) with an average weight of 64.1 ± 3.4 g. clove oil was used in concentrations of 14, 35, 56, 77, 98 and 119 mg/l, and those...

Radiation therapy has been used in cancer treatment for many decades; although effective in killing tumor cells, ROS produced in radiotherapy threaten the integrity and survival of surrounding normal cells. Recent studies have indicated that some commonly used medicinal plants may be good sources of potent but non-toxic radioprotectors. The pomegranate, Punica granatum L., an ancient, mystical,...