OBJECTIVE Jaundice is a common problem in neonatal period. Phototherapy is the most common treatment for neonatal jaundice. The purpose of this study was to determine the effect of adding white plastic cover around the phototherapy unit on hyperbilirubinemia in full term neonates with jaundice. METHODS In this randomized controlled trial, over 12 months (October 2009 - September 2010), 182 te...

Objective: We aimed to investigate the effect of phototherapy on plasma alpha-melanocyte-stimulating hormone (α-MSH) levels newborns with indirect hyperbilirubinemia (IHB) for first time. Materials and Methods: A total 45 cases, who were hospitalized in neonatal intensive care units between July 1, 2019, September 30, received phototherapy, retrospectively included study. Plasma α-MSH bilirubin...

This study is to determine the expression pattern of human UGT1A family enzymes in human skin. This study revealed a protective role of UGT1A1 expressed in the skin against neonatal hyperbilirubinemia. Sunlight, a natural and free source of light, makes it possible to treat neonatal jaundice without phototherapy units while allowing mothers to breast-feed neonates.

OBJECTIVE Newborns who suffer from jaundice and/or receive phototherapy (PT) are at a higher risk of developing asthma. In this study we aimed to investigate the relationship between bilirubin and peripheral eosinophil counts in newborns with severe hyperbilirubinemia needing PT. METHODS In this study, a retrospective analysis was performed on 306 newborns with severe hyperbilirubinemia with ...

Background: Hyperbilirubinemia and feeding problems are the most common indications for readmission in the first 2 weeks of life. Inadequate oral intake causes weight loss and increases the bilirubin enterohepatic circulation Objective: To describe the association between total serum bilirubin (TSB) levels and weight loss in healthy term infants readmitted for hyperbilirubinemia after birth. Me...

Background Several agents have been used for the treatment of neonatal hyperbilirubinemia, but the effect of oral fenofibrate on serum bilirubin level was not evaluated so much. The aim of this study was to assess the effect of oral fenofibrate on a total serum bilirubin (TSB) in term neonates with hyperbilirubinemia. Materials and Methods: This clinical trial was done on 80 term neonate with ...

infant jaundice is observed during the first week of life in approximately 60% of term and 80% of preterm infants. hyperbilirubinemia may lead to the development of kernicterus, hearing loss, and convulsion. the goal of therapy in hyperbilirubinemia is lowering blood bilirubin levels or at least preventing its increase. it is recommended that phototherapy and if unsuccessful, blood exchange tra...

Background/aim: The aim of this study is to determine the value questions asked in routine follow-up, cord blood bilirubin (CBB) and bilirubin/albumin (B/A) ratio estimating risk developing hyperbilirubinemia. Materials methods: Term healthy 217 newborns whose CBB albumin could be obtained needed measured level at 24th 72nd hours life were included. Nutrition, sex nationality, consanguinity bet...

Aim: Indirect neonatal hyperbilirubinemia is a common disorder worldwide which can remain benign if prompt management available. However there higher morbidity and mortality risk in settings with limited access to diagnosis care. The aim of this study was evaluate the etiologies indirect hyperbilirubinemia, determine effectiveness phototherapy treatment specify associated factors for prolonged ...

OBJECTIVE: To discuss the use of alternative treatment methods in hemolytic disease of newborn to replace common early exchange transfusion. METHODS: Case report of newborn with intensive Rh incompatibility treated with intensive phototherapy, plus phenobarbital instead of traditional early exchange transfusion.RESULTS: The neonatés cord blood showed 9.2 mg/dL of total bilirubin and 39% hematoc...