thrombocytopenia has been reported as a complication of phototherapy. in this study the effect of conventional phototherapy on platelet count was studied in 101 newborns with indirect hyperbilirubinemia, out of whom 50 patients (49.5%) had decreased levels of platelets; 20 (19.8%) of the latter had a platelet count of below 100000/mm3. decreased platelet count was maximum during the first 24 ho...

OBJECTIVE To describe photosensitization after prenatal exposure to a toxic amount of methylene blue and to alert pediatricians that, in a review of the literature, photosensitization (which this dye is capable of) has not been reported as a complication of prenatal exposure. DESIGN AND PATIENTS A descriptive report of physical findings and significant laboratory tests in a very low birth wei...

OBJECTIVES The American Academy of Pediatrics provides little guidance on when to discontinue phototherapy in newborns treated for hyperbilirubinemia. We sought to develop a prediction rule to estimate the probability of rebound hyperbilirubinemia after inpatient phototherapy. METHODS Subjects for this retrospective cohort study were infants born in 2012 to 2014 at ≥35 weeks' gestation at 16 ...

OBJECTIVE To compare the effectiveness of single (1 panel) vs. double (2 panels) phototherapy in reducing nonhemolytic hyperbilirubinemia in term newborns. METHODS Term newborns with hyperbilirubinemia were prospectively randomized to receive double or single phototherapy. Bilirubin levels were measured at admission and at 12-hour intervals, as well as at a follow-up 48 hours after discharge....

Phototherapy is a standard treatment for neonatal hyperbilirubinemia. During phototherapy, since photoproducts that cause the decrease in serum bilirubin are eliminated bile and urine, so adequate hydration should enhance effectiveness of phototherapy.

BACKGROUND Hyperbilirubinemia of the newborn is common. Rarely is an underlying disease other than physiologic hyperbilirubinemia considered the cause of high bilirubin levels. Some of the laboratory tests recommended by the American Academy of Pediatrics are expensive and do not always lead to diagnosis. OBJECTIVE To evaluate the efficacy of standard laboratory tests performed on newborn inf...

background: hyperbilirubinemia is the single most common abnormal physical finding in the first week of life and is commonly managed by phototherapy with its inherent complications.  a lesser known complication of the phototherapy is hypocalcemia.   objective: to study the prevalence of phototherapy-induced hypocalcemia and to compare it between premature and full-term babies.   methods: this s...

This study was conducted to determine the incidence and magnitude of post-phototherapy bilirubin rebound in neonates. Subjects included inborn neonates needing phototherapy for hyperbilirubinemia. Standard guidelines were used to start and stop phototherapy. Rebound bilirubin was measured 24+/-6 h after stopping phototherapy. Significant bilirubin rebound (SBR) was defined as post-phototherapy ...

From 105 808 neonates born at ≥35 weeks’ gestation at 1 of 17 Kaiser Permanente Northern California hospitals between 2012 and 2014, Chang et al 9 identified a cohort of 7048 newborns treated with phototherapy. The objective of the study was to identify predictors of “rebound, ” defined as a return to treatment threshold levels within 72 hours of discontinuation of a neonate’s first round of ph...