BACKGROUND There have been sporadic reports of hypersensitivity reactions to plants of the Cannabinaceae family (hemp and hops), but it has remained unclear whether these reactions are immunologic or nonimmunologic in nature. OBJECTIVE We examined the IgE-binding and histamine-releasing properties of hashish and marijuana extracts by CAP-FEIA and a basophil histamine release test. METHODS T...

Calprotectin, also known as S100A8/A9, has been linked to gut inflammation caused by IgE-mediated food hypersensitivities, but the pathophysiologic abnormalities it causes remain to be determined. We created a mild food hypersensitivity model through oral gavage of ovalbumin in Norway brown rats without using immune adjuvant. Changes in the levels of calprotectin and inflammation-associated cyt...

BACKGROUND Parthenium dermatitis is a major problem in urban and rural India. Patients with severe allergic rhinitis due to exposure to pollens of parthenium are reported to have parthenium specific IgE and IgG antibodies. Parthenium induces contact dermatitis by Type IV hypersensitivity and allergic rhinitis by Type-I hypersensitivity. AIMS The study was undertaken to detect Type-I and Type-...

Immediate hypersensitivity reaction to latex was first reported in Germany in 1927'. The next report appeared 1ll 1979 when Nutter2 described a case of contact urticaria due to the use of household gloves. Since then, there has been considerable increase in the number of reported cases of immediate type hypersensitivity to latex products. The clinical manifestations of the allergic reaction con...

allergen immunotherapy involves the administration of gradually increasing quantities of specific allergens to patients with ige-mediated conditions until a dose is reached that is effective in reducing disease severity from natural exposure. in the present study we evaluated a period of six years immunotherapy allergic rhinitis and allergic asthma patients with positive skin prick test of comm...

Immunoglobulin E (IgE) is ordered as the least abundant, but in many regards, most potent, of enormous antibody classes found mammals. IgE mediates reactions type 1 hypersensitivity allergic. Generally, plasma levels are very low with 100,000-fold than those G. However, these could be obviously increased specific conditions allergy, such bronchopulmonary aspergillosis, or case parasitic disease...

To evaluate type I hypersensitivity to grain dust (GD), its prevalence and relationship to respiratory dysfunction, we studied clinical and immunologic features, including skin prick tests (SPT), serum specific IgE, and bronchoprovocation tests of 43 employees working in the animal feed industry. To further characterize IgE-mediated reaction, SDS-PAGE and electroblot studies were performed. Our...

Introduction Food allergic reactions are due to an immune response to specific food components, allergens, that are commonly glycoproteins or other proteins or, rarely, carbohydrates. The most frequent allergic reactions are immediate hypersensitivity reactions mediated by antibodies (IgE) to food allergens. These antibodies circulate in the blood and are unique in that they can attach to mast ...

IgE-mediated hypersensitivity refers to immune reactions that can be rapidly progressing and, in the case of anaphylaxis, are occasionally fatal. To that end, identification of the associated allergen is important for facilitating both education and allergen avoidance that are essential to long-term risk reduction. As the number of known exposures associated with anaphylaxis is limited, discove...

Drug allergy to antibiotics may occur in the form of immediate or non-immediate (delayed) hypersensitivity reactions. Immediate reactions are usually IgE-mediated whereas non-immediate hypersensitivity reactions are usually non-IgE or T-cell mediated. The clinical manifestations of antibiotic allergy may be cutaneous, organ-specific (e.g., blood dyscracias, hepatitis, interstitial nephritis), s...