allergy to wheat is a common food allergy. in spite of this fact, there is not enough literature regarding the features and outgrowing of this allergy. the objective of this study was to evaluate the manifestations of this allergy and to follow the patients to evaluate whether outgrowing allergy happens again and when it occurs. eight wheat allergic patients diagnosed between 2000 and 2001 were...

BACKGROUND Drug hypersensitivity is classically divided into IgE mediated and non-IgE mediated disease. We report a rare case of consequent IgE mediated and non-IgE mediated reactions within the beta lactam class of antibiotics. CASE SUMMARY An 84-year-old man developed toxic epidermal necrolysis (TEN) due to ceftriaxone, a third generation cephalosporin, involving 72% of the body surface are...

Abstract Purpose of review In the recent years, more cases poultry meat allergy, both IgE- or non-IgE-mediated, are being reported. Patients have varied clinical reactivity at various levels sensitivity to different preparations. The lack validated biomarkers renders accurate diagnosis challenging. this review, we aim provide an overview current status allergy along with a description on allerg...

ige-mediated cell signaling, induced by cross-linking of high affinity receptor for ige (fcεri) in the presence of antigen (ag), is a well known mechanism described for mast cell activation in allergy and hypersensitivity reactions, which induces a spectrum of cellular responses such as secretion and up-regulation of cell surface fcεri. although for several years  ige  binding  to  fcεri  was  ...

Abstract Mast cells play a critical role in the effector phase of immediate hypersensitivity and allergic reactions. Propolis exerts multiple biological effects exhibits immunomodulatory antioxidant properties. However, its antidinitrophenyl (DNP) immunoglobulin E (IgE)-activated mast has not been investigated. In this study, we examined mechanism underlying inhibitory effect propolis (Unibee p...

BACKGROUND Cross-reactivity between penicillins or cephalosporins and carbapenems is anticipated as all have a beta lactam ring. However, the true incidence of immunoglobulin (Ig)E-mediated cross-reactivity is not known. METHODS A systematic review was conducted to collect and combine all published data on children and adults reported to have a clinical history of IgE-mediated hypersensitivit...

Food allergic reactions have generated increasing concern in the United States, with approximately one fourth of American households altering their dietary habits because a member of the family is perceived to suffer from food allergies. IgE-mediated (type I) hypersensitivity accounts for most well-characterized food allergic reactions, although non-IgE-mediated immune mechanisms are believed t...