background: we evaluated the effect of the ethanolic extract of scrophularia striata on the iranian strain of leishmania major (mrho/ir/75/er) both in vitro and in vivo conditions methods: the effective dose (ed) of ethanolic extract of s. striata were determined using  mtt assay  on the growth of promastigote forms of  l. major in axenic culture media. then, the ed 50 of  s. striata on mice pe...

introduction: urine morphine test, in several countries is the most primarily available qualitative test for detecting opioid abusers. since the users of illicit drugs attempt to defeat urine tests and there are also plenty of claims that usage of hd (high dose) contraceptive pills can result in false-negative results, we decided to design the present study to investigate the probable in vitro ...

background: the fundamental principles of internal targeted alpha therapy for cancer were established many decades ago.the high linear energy transfer (let) of alpha radiation to the targeted cancer cellscauses double strand breaks in dna. at the same time, the short range radiation spares adjacent normal tissues. this targeted approach complements conventional external beam radiotherapy and ch...

background: radioprotective efficacy of prunus avium fruit extract (pae) rich in vitamin a, c, e and anthocyanin was studied against radiation induced biochemical alterations in mice brain. materials and methods: in-vitro assays were performed with pae for its antioxidant studies thereafter for in-vivo study, swiss albino mice were divided into five groups. group 1 (control) normal mice. group ...

The chemical shift sensitivity and significant signal enhancement afforded by laser-polarized 129Xe have motivated the application of 129Xe NMR to biological imaging and spectroscopy. Recent research done by our group has used laser-polarized 129Xe in biomolecular assays that detect ligand-binding events and distinguish protein conformations. The successful application of unfunctionalized and f...