Here, we present the draft genome sequence of Saccharomyces cerevisiae BG-1, a Brazilian industrial strain widely used for bioethanol production from sugarcane. The 11.7-Mb genome sequence consists of 216 scaffolds and harbors 5,607 predicted protein-coding genes.

Glycerol production by Saccharomyces cerevisiae, which is required for redox-cofactor balancing in anaerobic cultures, causes yield reduction in industrial bioethanol production. Recently, glycerol formation in anaerobic S. cerevisiae cultures was eliminated by expressing Escherichia coli (acetylating) acetaldehyde dehydrogenase (encoded by mhpF) and simultaneously deleting the GPD1 and GPD2 ge...

Rice wine fermentation represents a unique environment for the evolution of the budding yeast, Saccharomyces cerevisiae. To understand how the selection pressure shaped the yeast genome and gene regulation, we determined the genome sequence and transcriptome of a S. cerevisiae strain YHJ7 isolated from Chinese rice wine (Huangjiu), a popular traditional alcoholic beverage in China. By comparing...

Strain selection and strain improvement are the first, and arguably most important, steps in the industrial production of biological compounds by microorganisms. While traditional methods of mutagenesis and selection have been effective in improving production of compounds at a commercial scale, the genetic changes underpinning the altered phenotypes have remained largely unclear. We utilized h...

The purpose of this investigation is to describe changes in industrial injury and disease rates in British Columbia between 1950 and 1996. Data on injury and disease rates were abstracted manually from WCB Annual Reports for the years 1950 through 1996. A number of interesting patterns emerge. Death report rates declined by 79% during the study period. Injury report rates also declined, althoug...

Proteases are the most studied microbial enzymes at commercial, industrial, pharmaceutical analytical, diagnostic, effluent abatement and other sectors. An effective proteolytic enzyme producing microbial strain has been isolated from marine soil under banana tree and evaluated its extracellular protease production properties with respect to different fermentative physiological parameters. The ...

21 In the industrial yeast biomass production process, cells undergo an oxidative and other 22 stresses which worsens the quality of the produced biomass. The overexpression of the 23 thioredoxin codifying gene TRX2 in a wine Saccharomyces cerevisiae strain increases 24 resistance to oxidative stress and industrial biomass production yield. We observed that 25 variations in the TRX2 gene dose i...

lipases are diversified enzymes in their properties and substrate specificity, which make them attractive tools for various industrial applications. in this study, an alkaline thermostable lipase producing bacteria were isolated from soil of different regions of isfahan province (iran) and its lipase was purified by ammonium sulfate precipitation and ion exchange chromatography. to select a the...