orthomixoviridae family viruses (influenza viruses) are major cause of death in human with respiratory diseases. although avian influenza in iranian chickens are associated with h9n2 subtype, there was not any study for h9n2 human infection as yet. this investigation conducted to serological study of h9n2 avian influenza infection in different human groups. the number of 334 blood sera includin...

avian influenza virus (aiv) infection is a major cause of bird or human mortality and morbidity, therefore the rapid identification of the virus is of important clinical and epidemiological implication. methods: a multiplex reverse transcriptase pcr (rt-pcr) was optimized for the detection of influenza a virus and the h5 and h9 subtypes. the influenza type a specific primers were directed to th...

background and aims: virus-like particles (vlps) have been suggested to be a promising recombinant vaccine approach. several studies have reported that the influenza vlps produced in insect cells is an effective vaccine candidate. due to crucial role of matrix m1 protein in assembly and budding of influenza particles, in all vlps structures, m1 protein have been considered as a main component. ...

results 111 female and 142 male were available from a total of 253 confirmed h1n1 cases. the minimum and maximum ages were 1.5 and 90 years, respectively. the most common symptoms were fever and cough. 144 cases had record of hospitalization, 100 cases were undergone outpatient treatment and nine cases have not recorded the treatment status. the most frequent underlying manifestation was hypert...

An experimental inactivated oil-emulsion H9N2 avian influenza vaccine was formulated with 3 parts ofinactivated avian influenza antigen A/Chicken/Iran/101/1998(H9N2) emulsified in 7 parts of oil adjuvant.Twelve week-old specific pathogen-free (SPF) chickens were divided into seven groups of 10 birds. Sixgroups were vaccinated with 1, 1/10th, 1/50th, 1/100th, 1/200th and 1/400th field dose of th...

background: influenza virus is the major cause of lower respiratory tract illnesses on the worldwide. vaccination can be an effective tool to prevent its outbreak. highly conserved viral nucleoprotein is an effective vaccine candidate to provide heterosubtypic immunity, offering resistance against various influenza virus strains. m aterials and methods: in present research np gene was inserted ...

background: the preventive measures against h1n1 influenza are vitally important. the aim of the present study was to assess the knowledge, attitude and performance of academic hospital staff about h1n1 influenza. methods: this study was carried out on ali-ebne-abiltaleb hospital staff in rafsanjan, iran. the data gathering tool was a researcher made questionnaire comprised of 38 questions on d...

There are many effective chemothereutic agents used in influenza disease which some of them inhibit virus replication by interfering with FluV (influenza virus) viral binding or its penetration into cell membrane. A series of polyoxometalates compounds such as POM-523 and PM-504 have been synthesized and have showed inhibitory effects on viruses. In this study we examined anti influenza activit...