Probiotic bacteria have been proposed as a therapeutic strategy for chronic intestinal inflammation and colon cancer. One of the mechanisms of action by which probiotics exert their effects is the modulation of apoptosis in intestinal immune and/or epithelial cells. Therefore, the knowledge of how probiotics modulate cell apoptosis provide additional information in the therapeutic strategy of t...

Previous immunohistochemical studies targeting the receptor tyrosine kinase (c-Kit) have demonstrated an apparent reduction in the number of gastrointestinal pacemaker cells--the interstitial cells of Cajal (ICC)--in horses with intestinal motility disorders. This study compared the level of transcription of the c-kit gene encoding this receptor in horses with and without such motility disorder...

The enteric nervous system (ENS) is derived from neural crest cells that migrate along the gastrointestinal tract to form a network of neurons and glia that are essential for regulating intestinal motility. Despite the number of genes known to play essential roles in ENS development, the molecular etiology of congenital disorders affecting this process remains largely unknown. To determine the ...

Over the last decades, the incidence of infestation by minor parasites has decreased in developed countries. Infectious agents can also suppress autoimmune and allergic disorders. Some investigations show that various protozoa and helminthes are connected with the main immune-mediated intestinal conditions including celiac disease (CD), inflammatory bowel diseases (IBD) and irritable bowel synd...

Patients with functional gut disorders, irritable bowel disease, and related syndromes frequently attribute their symptoms to intestinal gas. While patients are usually convinced of their interpretation, the doctor has few arguments to confirm or refute it, and in this context intestinal gas has become a myth. Studies of intestinal gas dynamics have demonstrated subtle dysfunctions in intestina...

Aim: The aim of the study is to evaluate Clinical profile & Prescribing Patterns Drugs in patients with gastrointestinal disorders. Materials and Methods: Patients who were diagnosed disorders either gender an age above 18 years included this study. Results: In our we have observed over 120 cases Gastro-Intestinal Disorders. All them suffering from Gastrointestinal 63.33% subjects Male 36.6...