background: ibs is the most common disorder diagnosed by gastroenterologists, which is seen in approximately 40-50% of patients seeking care from a specialist. several randomized controlled trials, have assessed the therapeutic effect of anti-depressant drugs, but there is not enough evidence to prove their effectiveness. materials and methods: fifty cases meeting rome ii criteria for ibs with ...

gluten associated disorders and the question around these associations has recently attracted attentions of many health professionals. this is because of high prevalence of undiagnosed gluten related disorders presenting with a multitude of symptoms and complications inside and outside small bowel. while the environmental factors associated with a complex genetics are leading to destructions of...

The article deals with chronic inflammatory processes of the intestines and their complications that contribute to gradual accumulation deep transmural lesions intestinal wall, including narrowings, development obstruction, abscesses, fistulas. Both bowel diseases lead onset diarrhea, abdominal pain, anemia caused by pathology. Detecting disease activity severity is crucial importance in treatm...

background: irritable bowel syndrome (ibs) is the most common disorder diagnosed by gastroenterologists seen in about 40-50% of patients seeking care from a specialist. ibs has been treated with selective serotonin reuptake inhibitors, but there is not enough evidence from controlled trials for their effectiveness. materials and methods: the aim of the study was to compare the effects of fluoxe...

There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular disease, and obesity.

the main inflammatory bowel disorders are including celiac disease (cd), inflammatory bowel diseases (ibd) and irritable bowel syndrome (ibs). celiac disease is a digestive and autoimmune disorder that can damage the small intestine and characterized by a multitude gastrointestinal (gi) and extra gi symptoms. ibd (including ulcerative colitis and crohn’s disease) is a group of inflammatory cond...

BACKGROUND Central nervous system (CNS) development and physiopathology are greatly affected by environmental stimuli. The intestinal barrier restricts the entrance of toxins, pathogens, and antigens while modulating the expression of various neuroactive compounds. The existence of a rich gut-to-brain communication raises the possibility that intestinal barrier alterations may take part in the ...