Question A 73-year-old male, referred by his GP with dyspepsia unresponsive to proton pump inhibitors. His past medical history included COPD, ischemic heart disease, Iron deficiency anaemia (IDA) investigated with colonoscopy and a colonic polyp removed 2012. In the absence of a clear treatable condition behind his IDA, his low Iron was treated with Iron supplement Ferrous Sulphate. His curren...

Dear Sir: We read with great interest the article by Patterson et al (1) published recently in the Journal. In the conclusion of their abstract, the authors purport to have shown that " in iron-deficient women of childbearing age, a high-iron diet produced smaller increases in SF [serum ferritin] than did iron supplementation but resulted in continued improvements in iron status during a 6-mo f...

Assessing vitamin and mineral supplement use is important because supplement use per se is an exposure of interest for the risk of several chronic diseases and because supplements contribute a large proportion of total (diet plus supplement) micronutrient intake, another important exposure in epidemiologic research. Unfortunately, little is known about methods for obtaining valid information ab...

The relationship between iron status and food iron absorption was evaluated in 75 normal volunteers, 15 patients with idiopathic hemochromatosis, and 22 heterozygotes by using double extrinsic radioiron tags to label independently the nonheme and heme iron components of a hamburger meal. In normal subjects, absorption from each of these pools was inversely correlated with storage iron, as measu...

BACKGROUND An independent Systematic Review Team performed a meta-analysis of 12 randomized, controlled trials comparing multiple micronutrients with daily iron-folic acid supplementation during pregnancy. OBJECTIVE To provide an independent interpretation of the policy and program implications of the results of the meta-analysis. METHODS A group of policy and program experts performed an i...

This study was performed to compare the dietary food and nutrient intakes according to supplement use in pregnant and lactating women in Seoul. The subjects were composed of 201 pregnant and 104 lactating women, and their dietary food intake was assessed using the 24-h recall method. General information on demographic and socioeconomic factors, as well as health-related behaviors, including the...

We investigated response sensitivities of indices of iron status to controlled iron depletion and repletion in 11 premenopausal women. The women were depleted of storage iron (as reflected by serum ferritin) through a combination of a low-iron diet and phlebotomy. They then consumed a diet containing 13.7 mg of iron per 2000 kcal, supplemented with either ascorbic acid or placebo (for 5 1/2 wee...

BACKGROUND Multiple micronutrient deficiencies during pregnancy in Vietnam may contribute to poor fetal growth and stunting, which are major determinants of the health and development offuture generations. OBJECTIVE We assessed the effects of prenatal multiple micronutrient supplementation on maternal weight gain during pregnancy, infant birthweight, and height of the child at around 2 years ...