نتایج جستجو برای: l arginine

تعداد نتایج: 638900  

Journal: :Molecular pharmacology 2001
A K Kiemer A M Vollmar

BACKGROUND The inducible nitric-oxide synthase (iNOS) synthesizes NO from L-arginine. Availability of L-arginine is maintained by a lipopolysaccharide (LPS)-induced induction of the CAT-2B amino acids transporter. Recently, we could show that the cardiovascular hormone atrial natriuretic peptide (ANP) inhibits the induction of iNOS in LPS-stimulated macrophages via its guanylate cyclase-coupled...

Journal: :international journal of fertility and sterility 0
sudha srivastava

background: lipid peroxidation is known to cause various impairments to sperm cells and may play a major role in the etiology of male infertility. asthenospermia is the main factor of male infertility and has significantly higher level of peroxidation than in normozoospermic males. materials and methods: using thiobarbituric acid (tba) assay procedure, we have determined the level of lipid pero...

Journal: :Gut 1996
F H Mourad L J O'Donnell E A Andre C P Bearcroft R A Owen M L Clark M J Farthing

BACKGROUND L-Arginine has been shown to induce fluid secretion in human jejunum. Nitric oxide, a derivative of L-arginine is thought to have an important role as an intestinal secretagogue. AIM To determine the effect of L-arginine and the nitric oxide synthase inhibitor, nitro L-arginine methyl ester (L-NAME), on fluid and electrolyte movement in rat jejunum. METHODS A 25 cm segment of rat...

ژورنال: دانشور پزشکی 2014
جلالی ندوشن, محمدرضا, حسنی, فاطمه, لک زایی, فاطمه, کرمی, منیژه ,

Background and Objective: Evidence exist that polycystic ovarian syndrome (PCOS) is responsible for a high percentage of women infertility during reproductive age. In this study, the correction of this problem by hyper-activation of nitric oxide (NO) system was studied in rats. Materials and Methods: Female Wistar rats (weighing 200-250 g) were kept as virgin diestrous under standard condit...

Alijan Ahmadi Ahangar, Durdi Qujeq, Mohsen Hosinian,

Changes in extra and intracellular neurotransmitter amino acids concentration in the early stage of acute cerebral ischemia have been reported. In this the study, serum level of gamma aminobutyric acid (GABA) and L-Arginine in acute ischemic stroke patients was assessed. 60 patients with acute ischemic stroke and sixthy healthy volunteers as a control group were assessed. Serum GABA was measure...

Journal: :journal of research in medical sciences 0
mohammad alizadeh student research committee, tabriz university of medical sciences, tabriz, iran. sevana daneghian student research committee, tabriz university of medical sciences, tabriz, iran. aida ghaffari student research committee, tabriz university of medical sciences, tabriz, iran. alireza ostadrahimi nutrition research center, department of nutrition, faculty of health and nutrition, tabriz university of medical sciences, tabriz, iran. abdolrasoul safaeiyan department of vital statistics and epidemiology, faculty of health and nutrition, tabriz university of medical sciences, tabriz, iran. rassul estakhri liver and gastrointestinal disease research center, tabriz university of medical sciences, tabriz, iran.

background: identifying new ways to decrease adiposity will be very valuable for health. the aim of this study was to find out whether l-arginine (arg) and selenium alone or together can increase the effect of hypocaloric diet enriched in legumes (hdel) on anthropometric measures in healthy obese women. methods: this randomized, double-blind, placebo-controlled trial was undertaken in 84 health...

Journal: :Hypertension 1992
L Lee R C Webb

This study characterizes the effects of L-arginine and NG-monomethyl L-arginine on dilator responsiveness of vascular tissue from Wistar-Kyoto rats and stroke-prone spontaneously hypertensive rats. Rings of abdominal aorta were suspended in tissue baths for measurement of isometric force. After contraction induced by phenylephrine, cumulative addition of acetylcholine, L-arginine, or A23187 to ...

Journal: :The Journal of clinical investigation 1991
P Y Chen P W Sanders

This study examined the contribution of nitric oxide (NO) to the susceptibility or resistance to the hypertensive effects of high sodium chloride (8.0% NaCl) intake in young Dahl/Rapp salt-sensitive (SS/Jr) and salt-resistant (SR/Jr) rats. Using NG-monomethyl-L-arginine (L-NMMA) as a probe for NO production in vivo, we found that increasing dietary sodium chloride increased NO activity in salt-...

2015
Karolina A.P. Wijnands Dennis M. Meesters Kevin W.Y. van Barneveld Ruben G.J. Visschers Jacob J. Briedé Benjamin Vandendriessche Hans M.H. van Eijk Babs A.F.M. Bessems Nadine van den Hoven Christian J.H. von Wintersdorff Peter Brouckaert Nicole D. Bouvy Wouter H. Lamers Anje Cauwels Martijn Poeze

Enhanced arginase-induced arginine consumption is believed to play a key role in the pathogenesis of sickle cell disease-induced end organ failure. Enhancement of arginine availability with L-arginine supplementation exhibited less consistent results; however, L-citrulline, the precursor of L-arginine, may be a promising alternative. In this study, we determined the effects of L-citrulline comp...

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