OBJECTIVE To assess the benefit of the periprostatic administration of lidocaine previously to ultrasound-guided prostate biopsy. MATERIALS AND METHODS In the period from April to October 2002, forty patients underwent ultrasound-guided prostate biopsy due to increased PSA or abnormal digital rectal examination. A randomized double-blind study was performed, where the patients received an inj...

In this study, solvent-cast polymeric films containing ionic liquid lidocaine/aspirin for transdermal patches were developed. Solvent-cast prepared from two polymers, pectin and Eudragit® NE 30D, by drying the solution in a hot air oven at 70 ± 3 °C 10 h. Glycerin was used as plasticizer. Lidocaine aspirin form loaded into patches. The physicomechanical properties of characterized texture analy...

Background: Articaine is an amide local anaesthetic, which is gaining popularity for use in dental and oral surgical anaesthesia in the United Kingdom. Hitherto there has been insufficient evidence to recommend articaine above the more commonly used lidocaine for dental procedures. The aim of this study is to compare the efficacy of 4% articaine with 1:100,000 adrenaline (4AA) with that of 2% l...

At the author’s institution, the use of buffered lidocaine before painful treatment procedures has increased dramatically over the past 4 years, and more than 4500 vials are now used each year. Most vials are used by the peripherally inserted central catheter (PICC) team for insertion of central lines, and the rest are used to aid in insertion of peripheral lines. The benefits of buffered lidoc...

introduction: many reports have shown that the grape (vitis vinifera) seed extract induces antioxidant, hypotensive hypolipidemic, and vasodilatory effects. we have recently shown the relaxatory effect of grape leaf extract on rat's aorta, ileum, uterus and frog's heart rate and contractility. the objective of this study was to investigate the spasmolytic effect of vitis vinifera leaf hydroalco...

Twenty-two patients undergoing total knee arthroplasty received combined sciatic plus femoral "3 in 1" blocks as adjuncts to general anaesthesia. Eleven patients received 0.375% bupivacaine 45 ml (168.75 mg) with adrenaline 1 in 200,000 and the remaining 11 received plain solution according to a previously prepared, randomized list. The mean maximum plasma bupivacaine concentration was signific...

(Received for publication, January 3, 1958) The relative noradrenaline content of the adrenal gland in young animals was larger than that in adult ones.') Therefore, it is of interest to know whether the relative activities of noradrenaline to adrenaline in young animals differ from those in adult ones. In this view, the pressor action of noradrenaline was compared with that of adrenaline in yo...