PURPOSE This study was designed to determine whether the amount of endochondral growth response to mechanical compression and the underlying growth mechanism differed with night-time or day-time loading, relative to full-time loading. METHODS Mechanical compression (nominally 0.1 MPa stress) was applied across tibial and tail vertebral growth plates of growing Sprague-Dawley rats. Four groups...

A rat model was used to distinguish between the different factors that contribute to muscle tissue damage related to deep pressure ulcers that develop after compressive loading. The separate and combined effects of ischemia and deformation were studied. Loading was applied to the hindlimb of rats for 2 h. Muscle tissue was examined using MR imaging (MRI) and histology. An MR-compatible loading ...

Ocular drug delivery through hydrogel contact lenses has great potential for the treatment of ocular diseases. Previous studies showed that the loading of lipophilic vitamin E to silicone-hydrogel contact lenses was beneficial in ocular drug delivery. We hypothesized that vitamin E loading to another type of popular hydrogel contact lenses, pHEMA-hydrogel contact lenses, improves ocular drug de...

objective: endothelium is a selective and permeable membrane for transferring nutrients and vital components to arterial wall. endothelial damage might lead to altered biological function of endothelium and clinical consequences such as atherosclerosis. blood pressure pulse always exerts circumferential tension to the arterial wall. hence, such tension together with other loads, play important ...

objectives : microbial leakage through the implant-abutment (i-a) interface results in bacterial colonization in two-piece implants. the aim of this study was to compare microleakage rates in three types of replace abutments namely snappy, goldadapt, and customized ceramic using radiotracing. materials and methods: three groups, one for each abutment type, of five implants and one positive and ...

A method for repeatable loading of propranolol hydrochloride as a model drug onto the ion exchanger Amberlite TM IRP69 was developed and different parameters for the loading process were evaluated due to their impact of the extent of loading. It was found that the extent of loading in equilibrium is widely independent of the experimental method used. However, a magnetic stirrer comminutes the i...

the rheological behavior of feedstocks used in powder injection molding technology influences strongly on the final properties of the products. powder loading is one of the important factors that have a great distribution on rheological behaviors. by using the gas atomized spherical 316l stainless steel powder and the binder of 55% paraffin wax+ 40% polyethylen+ 5% stearic acid, four kinds of f...

Twente. Beta is the largest research centre in the Netherlands in the field of operations management in technology-intensive environments. The mission of Beta is to carry out fundamental and applied research on the analysis, design, and control of operational processes.