Several innate and adaptive immune cell types participate in ischemia/reperfusion induced tissue injury. Amongst them, platelets have received little attention as contributors in the process of tissue damage after ischemia reperfusion (I/R) injury. It is currently unknown whether platelets participate through the immunologically important molecules including, CD40 and when activated, CD154 (CD4...

Progressive collapse is a situation where local failure of a primary structural component leads to the collapse of adjoining members which, in turn, leads to additional collapse. Hence, the total damage is disproportionate to the original cause. The most common local failure in framed structure is assumed to be column failure. In this paper, a new approach for dynamic column removal in framed s...

Peridynamics (PD) is a nonlocal continuum theory based on integro-differential equations without spatial derivatives. The elongation fracture criterion is implicitly incorporated in the PD theory, and fracture is a natural outcome of the simulation. On the other hand, a new fracture criterion based on the crack opening displacement combined with peridynamic (PD-COD) is proposed. When the relati...

This paper advances a growing body of mobile mapping work which captures building scale tornado damage in order to reveal vulnerabilities, or protections, within an otherwise apparently homogenous damage path. The hope is to find how micro geography, or built environment structure patterning might lead to policy advances with regards to rebuilding of critical infrastructure in tornado prone are...

A study on fatigue damage characterization for long fibre epoxy composites is here presented. The main aim is to calculate with full field technique the local damage experimental parameters, in order to express the material damage state and to validate a procedure for the localization of the probable zones of failure. It is well known that fatigue damage evolves mainly in some localized areas a...

nowadays, as a result of increased terrorist and bomb attacks throughout the globe in the vicinity of strategic buildings, designing these structures against impact loads, particularly the blast-related ones, has been taken into more consideration. the current procedure for designing the structure against an explosion is a design against the local failure of the current elements in the first st...

Deer (Cervidae) cause considerable damage to forest plantations, crops, and protected habitats. The most common response to this damage is to implement strategies to lower population densities. However, lowering deer density may not always be desirable from hunting, recreational, or conservation perspectives. Therefore, knowledge is needed about additional factors beyond deer density that affec...

Unpredicted loading caused by blast or impact may lead to severe damage in structures. Such damage may affect the whole structural performance. Connections are the key contributor to the integrity and energy dissipation capacity of the structural steel systems and play the most important role in mitigating such consequences. In the view of the importance of connections, finite element analysis ...

Permanent nerve involvement following inferior alveolar nerve block may occur from 1 in 20,000 to 850,000 patients with little information on local anesthetic used. Patients with permanent nerve damage from blocks were recorded. Lidocaine was associated with 35 percent, with articaine causing approximately 30 percent of the cases. Nerve blocks can cause permanent damage to the nerves, independe...