OBJECTIVE To investigate the effectiveness of GnRH antagonist multiple-dose protocol (MDP) with oral contraceptive pill (OCP) pretreatment in poor responders undergoing IVF/ICSI, compared with GnRH antagonist MDP without OCP pretreatment and GnRH agonist low-dose long protocol (LP). METHODS A total of 120 poor responders were randomized into three groups according to controlled ovarian stimul...

The aim of this study was to investigate the relationships among the ages of patients, serum progesterone (P) levels on the day of human chorionic gonadotropin administration (DHCG), and clinical pregnancy rates in a gonadotropin-releasing hormone (GnRH)-agonist long protocol. A total of 5,566 patients followed at the reproductive medicine center of a tertiary care public hospital who were unde...

The induction of long-term potentiation (LTP) and long-term depression (LTD) of excitatory postsynaptic currents was investigated in proximal synapses of layer 2/3 pyramidal cells of the rat medial prefrontal cortex. The spike timing-dependent plasticity (STDP) induction protocol of negative timing, with postsynaptic leading presynaptic stimulation of action potentials (APs), induced LTD as exp...

Purified human menopausal gonadotropin (HMG) is a natural product extracted from the urine of postmenopausal women that contains pituitary follicle-stimulating hormone (FSH), luteinizing hormone (LH), and a small amount of human chorionic gonadotropin (HCG). Here we retrospectively conducted a clinical pharmaceutical study on a cohort of normogonadotropic infertile patients addressed to long Gn...

purpose: to assess whether bromocriptine-rebound method (brm) can improve pregnancy   outcomes compared to long protocol after intracytoplasmic sperm injection cycles (icsis).   materials and methods: a total of 114 women underwent icsi. pregnancy outcomes and   hormonal data were compared between two groups, i.e. long protocol and brm. ovulatory   women with normal serum prolactin levels were ...

background: c-reactive protein (crp) can be increased after hormonal stimulations. the changes of crp might affect the success of in-vitro fertilization (ivf). objective: the aim of this study was to determine the possible relationship between the serum crp level and outcome of controlled ovarian stimulation, and pregnancy rate in patients undergoing ivf or intra cytoplasmic sperm injection (ic...

background: smoking has negative effects on reproductive process. exposing to cigarette smoking (passive smoking) may exert some effects as the direct smoking. objective: the aim of this study was to evaluate the correlation between ovarian response and passive smoking in women who underwent art cycles. materials and methods: one hundred-sixty patients who underwent icsi between 2000 and 2001 w...

background: although the uterine fibroids are common, their influence on fertility remains controversial. the association of submucosal fibroid with subfertility is well recognized, but debate persists as to whether intramural fibroids can cause infertility and the evidence for its effect on pregnancy in cycles of assisted conception remains unclear. objective: the purpose of present study was ...

OBJECTIVE To study the correlation between stimulation duration of IVF cycles, with and without GnRH agonist (GnRH-a), and cycle outcome. DESIGN Retrospective analysis of data. SETTING University-affiliated IVF clinic. PATIENT(S) 998 IVF cycles in which long GnRH-a protocol was used, and 155 cycles with hMG only. INTERVENTION(S) IVF cycles. MAIN OUTCOME MEASURE(S) Cycle outcome in num...