Longevity in Okinawa is considered to be a result of traditional low calorie diet. Le Bourg suggests that Okinawa is an example of severe malnutrition, which is harmful for later generations. We believe that current loss of longevity advantage in Okinawa is a result of diet westernization and that the dietary restriction is a valid way of life extension in humans.

BACKGROUND Human leptin is a peptide hormone that is released from white adipocytes. The absence of leptin or its receptor leads to uncontrolled food intake, leading to obesity. In the present work, the effects of auricular acupressure combined with low-calorie diet on the leptin hormone level were investigated. METHODS Volunteers (n=86) with body mass indices (BMI) between 25 and 45 kg/m² we...

Maintenance of weight loss remains an obstacle in successful treatment of obese individuals. The long term impact of calorie restriction on adipose tissue biology is poorly characterized. Molecular and lipid markers of these processes may provide wider understanding in the mechanisms underlying weight control. We aimed at identifying relevant relationship between clinical traits, clusters of ge...

Vol. 20 Calorie balance in man observations have recently been repeated in another obese patient who received the diets in the reverse order (Table z). Each diet was given for 4 days and the biological assay was carried out on urine collected during the last z days of each dietary period. Ketogenic activity was present in the urine in the periods of low-carbohydrate diets and disappeared when t...

BACKGROUND The prevalence of micronutrient deficiencies is higher in obese individuals compared to normal-weight people, probably because of inadequate eating habits but also due to increased demands among overweight persons, which are underestimated by dietary reference intakes (DRI) intended for the general population. We therefore evaluated the dietary micronutrient intake in obese individua...

Low carbohydrate diets are currently being promoted as an effective treatment for weight reduction. The most popular, the Atkins’ diet, is a worldwide bestseller with over 10 million book copies sold (the earliest being Dr Atkins’ New Diet Revolution). Two randomised clinical trials in obese patients have shown effective weight loss at six months on the Atkins’ diet compared with a low fat calo...

BACKGROUND & AIMS We determined the effects of acute and chronic calorie restriction with either a low-fat, high-carbohydrate (HC) diet or a low-carbohydrate (LC) diet on hepatic and skeletal muscle insulin sensitivity. METHODS Twenty-two obese subjects (body mass index, 36.5 +/- 0.8 kg/m2) were randomized to an HC (>180 g/day) or LC (<50 g/day) energy-deficit diet. A euglycemic-hyperinsuline...

Objective(s) The aim of this study was to investigate the effects of aerobics, pilates exercises and low calorie diet on leptin levels and some lipid profiles and anthropometric factors in sedentary women. Materials and Methods Forty six women (age 36.41±3.47) were recruited and divided into four groups: aerobic exercise group (EX), Pilates exercise group (Pilates), low calorie diet (LCD) an...