Giant cell tumor (GCT) is a primary and benign tumor of bone, albeit locally aggressive in some cases, such as in the epi-metaphyseal region of long bones, predominantly the distal end of femur and proximal end of tibia (1). There are a variety of treatments for a bone affected by GCT, ranging from chemotherapy, radiotherapy, embolization, and cryosurgery, to surgery with the use of chemical or...

Rapid bone defect filling with normal bone is a challenge in orthopaedics and dentistry. Strontium ranelate (SrRan) has been shown to in vitro decrease bone resorption and increase bone formation, and represents a potential agent with the capacity to accelerate bone defect filling. In this study, bone tibial defects of 2.5 mm in diameter were created in 6-month-old female rats orally fed SrRan ...

RATIONALE Inflammatory pseudotumor has been commonly reported in patients undergoing total hip arthroplasty (THA). PATIENT CONCERNS We reported a patient who had a massive intra-pelvic pseudotumour and acetabular bone defect underwent two-stage revision THA. DIAGNOSES A new surgical strategy for pseudotumor after THA is performed. INTERVENTIONS Thorough debridement intra-pelvic pseudotumo...

Humeral shaft nonunions with severe osteopenia presents challenges. Because of previous surgeries, complex anatomy of vascular, muscles and nerves at the nonunion site making the operation difficulty and risky. Vascularized fibula transfer and bone transporting are particularly useful in handling bone loss. However both methods require surgical experience and facility which are not available in...

We report 2 cases of congenital pericardial defect with ruptured acute type A aortic dissection. Case 1: An 83-year old man presented with sudden chest and back pain, and computed tomography (CT) showed acute aortic dissection with left pleural massive effusion. Because of his unstable haemodynamic condition with low blood pressure, an emergency operation was performed. We observed small amount...

The successful treatment of an established pseudarthrosis in a forearm bone is always difficult, especially when the skin or soft tissues have been damaged by previous injury or infection. The usual technique is by the use of massive onlay grafts, as advised by Henderson (1938), Campbell (1939) and Speed (1942). In my experience this method, using a tibial graft, has had only moderate success i...

In the Results section under subheading 'Longitudinal in vivo assessment of biomaterial-induced bone formation' " Over the following 8 weeks the plural stayed closed. " should read: " Over the following 8 weeks the defects stayed closed ". Under subheading 'Temporal and spatial in vivo assessment of hydroxyapatite deposition during bone defect regeneration – anterior-posterior axis. ' " Thereaf...