OBJECTIVE The passage of ionizing radiation in living cells creates clusters of damaged nucleotides in DNA. In this study, DNA strand breaks induced by the beta particle of iodine-131 (I-131), have been determined experimentally and compared to Monte Carlo simulation results as a theoretical method of determining(131)I damage. MATERIALS AND METHODS In this experimental study, in order to crea...

The increasing availability of SPECT/CT devices with advanced technology offers the opportunity for the accurate assessment of the radiation dose to the biological target volume during radionuclide therapy. Voxel dosimetry can be performed employing direct Monte Carlo radiation transport simulations, based on both morphological and functional images of the patient. On the other hand, for voxel ...

abstract background: accurate methods of radiation therapy dose calculation. there are different monte carlo codesfor simulation of photons, electrons and the coupled transport of electrons and photons. mcnpis a general purpose monte carlo code that can be used for electron, photon and coupledphoton-electron transport.monte carlo simulation of radiation transport is considered to be one of the ...

Due to intensive use of multileaf collimators (MLCs) in clinics, finding an optimum design for the leaves becomes essential. There are several studies which deal with comparison of MLC systems, but there is no article with a focus on offering an optimum design using accurate methods like Monte Carlo. In this study, we describe some characteristics of MLC systems including the leaf tip transmiss...

*Corresponding author: Dr. Asghar Mesbahi, Medical Physics Department, Medical School, Tabriz University of Medical Sciences, Tabriz, Iran. Fax: +98 411 3364660 Email: [email protected] Background: Prediction of the absorbed dose in irradiated volume plays an important role in the outcome of radiotherapy. Application of small fields for radiotherapy of thorax makes the dose calculation pr...

*Corresponding author: Dr. Mohammad Amin Mosleh-Shirazi, Department of Radiotherapy and Oncology, Shiraz University of Medical Sciences, Shiraz, Iran. Fax: +98 711 6474320 E-mail: [email protected] Background: The dose rate distribution delivered by a low dose rate 137Cs pellet source, a spherical source used within the source trains of the Selectron gynecological brachytherapy system, was inv...

background: the monte carlo (mc) method is not only used for dose calculations around brachytherapy sources but also for benchmarking treatment planning systems (tps) calculations. materials and methods: three 60co sources of gzp6 brachytherapy unit were simulated using mcnp4c mc code. the radial dose functions were calculated by mc method and gzp6 tps and were compared. results: there was a go...