نتایج جستجو برای: memory disorders
تعداد نتایج: 874148 فیلتر نتایج به سال:
اثر تجویز توأم دونپزیل و اسید فولیک بر اختلالات حافظه فضایی در موش صحرایی نر بالغ مدل بیماری آلزایمر
Background: Alzheimer's disease is a neurodegenerative disorder that is diagnosed with a lack of memory and perception. Objective: The aim of this study was to evaluate the effect of donepezil and folic acid on reference and working memory disorders caused by electrical lesion of nucleus basalis magnocellularis (NBM). Methods: In this experimental study, 49 adult male Wistar rats were divided...
Introduction: Mercury, in different form can induce adverse effects on various organs especially central nervous system. The aim of this study was to determine concentration of mercury in inhalation and urine of the exposed worker and to investigate the prevalence of probable neurobehavioral disorders. Material and Method: The present case-control study was conducted among workers of a un...
Dysfunctions in hypothalamic-pituitary-adrenal (HPA) axis have been reported for several mental disorders that are also often characterized by memory disturbances. It is now well established that glucocorticoids influence cognitive processes by enhancing memory consolidation and impairing memory retrieval. There is further evidence for an association between HPA axis related disturbances and me...
The aim of the present study was to examine the hypothesis that miR-33-5p attenuates morphine state-dependent (StD) memory via the µ opioid receptor by regulating cyclic AMP response element-binding protein (CREB). The effects of post-training morphine and morphine StD memory and their interaction with pre-test naloxone were evaluated using a single-trial inhibitory avoidance paradigm. Then, th...
Introduction: Previous findings from our laboratory indicated that exercise alleviates the deficits in cognitive and anxiety disorders in healthy female rats. But the effect of exercise on cognitive and anxiety disorders induced by chronic morphine in experimental monopose of rats (ovariectomized) not known. Aim of this study was to investigate the effects of mild and modorate forced exercise o...
Verapamil is a drug that blocks L-type calcium channels and selectively inhibits calcium ion entry into the central and peripheral nervous system cells. Verapamil is used acutely and chronically in treatment of some cardiovascular and central nervous system disorders. It has also been shown that acute administration of verapamil has no significant effect on learning and memory in rats, but the ...
Memory formation requires de novo protein synthesis, and memory disorders may result from misregulated synthesis of critical proteins that remain largely unidentified. Plasma membrane ion channels and receptors are likely candidates given their role in regulating neuron excitability, a candidate memory mechanism. Here we conduct targeted molecular monitoring and quantitation of hippocampal plas...
Welcome to the second in our two-part special issue on the electrophysiology of memory. In the first installment, we included papers reviewing recent findings from studies addressing basic questions about human memory processes. In this issue, we will consider electrophysiological studies of memory processes in special populations. As Gabriel Garcia Marquez stated in his epigraph to Living to T...
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