Suppose that a finite group G admits a Frobenius group of automorphisms FH with kernel F and complement H such that the fixed-point subgroup of F is trivial: CG(F ) = 1. In this situation various properties of G are shown to be close to the corresponding properties of CG(H). By using Clifford’s theorem it is proved that the order |G| is bounded in terms of |H| and |CG(H)|, the rank of G is boun...

Tsetse flies are the sole vectors of Trypanosoma brucei parasites that cause sleeping sickness. Our knowledge on the early interface between the infective metacyclic forms and the mammalian host skin is currently highly limited. Glossina morsitans flies infected with fluorescently tagged T. brucei parasites were used in this study to initiate natural infections in mice. Metacyclic trypanosomes ...

We have cloned and sequenced a cDNA for a metacyclic trypomastigote-specific glycoprotein with a molecular mass of 90 kDa, termed MTS-gp90. By immunoblotting, antibodies to the MTS-gp90 recombinant protein reacted exclusively with a 90-kDa antigen of metacyclic trypomastigotes. The insert of the MTS-gp90 cDNA clone strongly hybridized with a single 3.0-kb mRNA of metacyclic forms, whereas the h...

In this study we examined whether the maintenance of Trypanosoma cruzi by long-time in axenic culture produces changes in gene expression and antigenic profiles. The studies were made with a Dm30L-clone from a low-virulent strain and a non-cloned virulent EP-strain of T. cruzi. Both parasites were maintained, for at least seven years, by successive alternate passage triatomine/mouse (triatomine...

The Dade group D(P ) of a finite p-group P , formed by equivalence classes of endopermutation modules, is a finitely generated abelian group. Its torsion-free rank equals the number of conjugacy classes of non-cyclic subgroups of P and it is conjectured that every nontrivial element of its torsion subgroup D(P ) has order 2, (or also 4, in case p = 2). The group D(P ) is closely related to the ...