Hepatocyte growth factor (HGF) induced scattering and cell migration of human gastric adenocarcinoma MKN-74. HGF also significantly promoted the growth of MKN-74 cells in a dose-dependent manner, although HGF is reported to be antiproliferative for the growth of tumor cell lines. This result indicates that HGF stimulates cell proliferation of not only normal epithelial cells but also certain ca...

The BL Lac object Mkn 501 was observed with the BeppoSAX satellite at three epochs in April-May 1998, simultaneously with the Whipple and HEGRA Cherenkov telescopes. The X-ray spectrum is well detected up to 70 keV and it exhibits, at all epochs, a continuous curvature, which is here modeled with three power-laws of increasingly steeper index at larger energies. In the νF ν representation the s...

We present photoionization modelling of the Extended Narrow Line Region (ENLR) in Mkn 79 based on long-slit spectra presented in our previous paper (Nazarova et al. 1996). The ENLR has been modelled with two gas components: a system of high density clouds embedded in a low density gas envelope. The ENLR line fluxes have been calculated allowing for attenuation of the nuclear ionizing continuum ...

Four new (1-4), along with six known (5-10) dihydro-β-agarofuran sesquiterpene polyesters were isolated from the whole plants of Parnassia wightiana. The new compounds were structurally elucidated through spectroscopic analysis including UV (Ultraviolet Spectrum), IR (Infrared Spectrum), ¹H-NMR (¹Hydrogen-Nuclear Magnetic Resonance), ¹³C-NMR (¹³Carbon-Nuclear Magnetic Resonance), DEPT (Distorti...

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) shows increased expression in a wide variety of human cancers, and its over-expression is associated with enhanced migration, invasion, and in vivo metastasis. Here, we reported that CEACAM6 was up-regulated in gastric cancer (GC) cell lines and tumor tissues. Over-expression of CEACAM6 in MKN-45 and SGC-7901 GC cells promoted ...

Observational and theoretical results indicate that low-redshift BL Lacertae objects are the most likely extragalactic sources to be detectable at TeV energies. In this paper we present the results of observations of 4 BL Lacertae objects (PKS0521 365, EXO0423.4 0840, PKS2005 489 and PKS2316 423) made between 1993 and 1996 with the CANGAROO 3.8m imaging Cerenkov telescope. During the period of ...

We present the expected variability features in the context of the Synchro-Self-Compton (SSC) model of emission from Active Galactic Nuclei (AGNs). We show that the homogeneous SSC model can describe well the observed mul-tiwavelength spectrum and variability of objects such as Mkn 421 and Mkn 501; however in order to explain the very fast flaring timescales occasionally observed from these obj...

This study examined whether human gastric carcinoma cells produced EGF for self-stimulation, using TMK-1 and MKN-28 cells which express mRNA for EGF and EGF receptor. EGF protein production was confirmed by ELISA and flow cytometric analysis. The lysates of these cells replaced EGF-induced biological activity to EGF receptor bearing KB cells but the culture supernatants did not. Furthermore, EG...