نتایج جستجو برای: morphea profunda
تعداد نتایج: 2289 فیلتر نتایج به سال:
INTRODUCTION Scleroderma is an autoimmune disease that involves the connective tissue characterized by skin fibrosis, classified as localized and systemic (participation of one or more internal organs). The primary objective of this study is to describe and analyze the clinical and laboratory findings in a group of children diagnosed with scleroderma at a referral hospital. MATERIAL AND METHO...
Morphea is a connective tissue disorder characterized by skin homogenization. No protocol of therapy is agreed upon, due to the variation in disease presentations as well as follows up methods. UVA-1 is an effective therapy due to deep penetration of the skin. The aim of the study was to evaluate the efficacy, safety and side effects of medium dose (30 J/cm ) UVA-1 phototherapy for the treatmen...
Anaerobic ammonium-oxidizing (anammox) bacteria are responsible for a significant portion of the loss of fixed nitrogen from the oceans, making them important players in the global nitrogen cycle. To date, marine anammox bacteria found in marine water columns and sediments worldwide belong almost exclusively to the 'Candidatus Scalindua' species, but the molecular basis of their metabolism and ...
BACKGROUND Colitis cystica profunda is a rare nonneoplastic disease defined by the presence of intramural cysts that contain mucus, usually situated in the rectosigmoid area, which can mimic various malignant lesions and polyps. Its etiology still remains not fully elucidated, and several mechanisms such as congenital, post-traumatic, and infectious have been implicated in the development of th...
Juvenile localized scleroderma, also known as morphea, is the more frequent subtype of scleroderma in childhood. It comprises a group of distinct conditions which involve the skin and subcutaneous tissues. They range from very small plaques of fibrosis involving only the skin, to diseases which may cause significant functional and cosmetic deformity. The most widely used classification divides ...
Generalized morphea is a disease characterized by wide-spread sclerosis of the skin. A 39-year-old man presented with history of multiple pigmented and bound-down plaques on the body along with mucosal involvement. Dermatological examination showed multiple indurated and sclerosed plaques with follicular plugging in few of them and gross thickened eroded and glazed tongue. The constellation of ...
Morphea and systemic sclerosis are fibrosing disorders of the skin that share common inflammatory and immunologic pathways that are responsible for the vascular changes, increased collagen production, and extracellular matrix proliferation seen in both conditions. Recent advances in molecular biology techniques have furthered our knowledge of the potential underlying pathogenic mechanisms and o...
Sir, A 21-year-old male presented with multiple brown asymptomatic plaques arranged in a zosteriform pattern, confined to the left flank of abdomen (Fig. 1) of 6 months’ duration. There was no history of herpes zoster affecting the same location. His general physical and systemic examinations were within normal limits. Cutaneous examination revealed a 3–6 cm wide zosteriform band composed of br...
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