نتایج جستجو برای: multidrug efflux pumps

تعداد نتایج: 54681  

Journal: :Agronomy 2022

Widespread resistance to QoIs, DMI and SDHIs fungicides has been reported for Brazilian populations of the wheat blast pathogen Pyricularia oryzae Triticum lineage (PoTl). A pre-existing mechanism not associated with target site mutations indicated DMIs SDHIs, strong indication that PoTl multidrugresistance (MDR). Therefore, main objective this study was test hypothesis SDHI detected in due eff...

2012
Diana Machado Isabel Couto João Perdigão Liliana Rodrigues Isabel Portugal Pedro Baptista Bruno Veigas Leonard Amaral Miguel Viveiros

Multidrug resistant (MDR) tuberculosis is caused by Mycobacterium tuberculosis resistant to isoniazid and rifampicin, the two most effective drugs used in tuberculosis therapy. Here, we investigated the mechanism by which resistance towards isoniazid develops and how overexpression of efflux pumps favors accumulation of mutations in isoniazid targets, thus establishing a MDR phenotype. The stud...

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