Total ... 28 grains injected. Collapse was passing off at 4 p. M. Urine was not passed, however, till morning of 28th : had reactionary fever, for which he was treated with quinine. Recovered. 3. At Sadr Dispensary.?Sahibdin, aged 35, Mussulman. 28th April.?10 A. M., was attacked yesterday morning. Is now in intense collapse : cramps severe. 28tli April, 10 A. M. injected G grs. Chloral. 2 P. M...

A 79-year-old woman had a habit to eat a mango every night before sleep and experienced muscle cramps during sleep. Her muscle cramps may be resulted from potassium overload due to overeating mangos.

RATIONALE Neutrophils have been reported to contribute to early atherosclerotic lesion formation. Mechanisms of neutrophil-driven atherosclerosis remain unclear so far. OBJECTIVE Investigation of the role of the neutrophil granule protein cathelicidin (CRAMP in mouse, LL37 in human) in atherosclerosis. METHODS AND RESULTS Compared to Apoe(-/-) mice, Cramp(-/-) Apoe(-/-) mice exhibit reduced...

A 10-year-old boy was evaluated for a 4-month history of muscle cramps. Initially, the cramps occurred twice weekly, usually in his calves. More recently, he had been having cramps in both arms and hands which lasted for up to 5 minutes. On occasion, his fi ngers would get “stuck” for several minutes before he could straighten them. Although he still participates in gym class, his mother report...

Sir, There has been a growing interest in the role of the cerebellum in primary dystonia. Although this role is not yet fully understood (Sadnicka et al., 2012), an elegant paper by Hubsch et al. (2013) in Brain showed that in writer’s cramp, a form of task-specific primary hand dystonia, the cerebellum has lost its ability to modulate sensorimotor plasticity of the motor cortex. As part of the...

The accuracy of administration of BoNT-A into the target muscle is primary to obtain a reduction of movement disorders in dystonia patients or spasticity in subjects with upper motor neuron syndrome. Indeed, incorrect needle placement can result in complete failure of treatment causing also weakness or paresis, particularly for small muscles of the hand and forearm in writer’s or musician’s cra...

Writer's cramp is a task-specific dystonia that leads to involuntary hand postures during writing. Abnormalities of sensory processing may play a pathophysiological role in this disorder. Electrophysiology studies in a monkey model of focal dystonia have revealed de-differentiation of sensory maps and the existence of single cells in hand regions of area 3b with enlarged receptive fields that e...

BACKGROUND Cathelicidin is a proposed defender against infection of the urinary tract via its antimicrobial properties, but its activity has not been delineated in a dedicated cystitis model. METHODS Female C57Bl/6 mice, wild type or deficient in cathelin-related antimicrobial peptide (CRAMP; an ortholog of the sole human cathelicidin, LL-37), were infected transurethrally with the cystitis-d...

BACKGROUND We identified cathelicidin related antimicrobial protein (CRAMP) secreted from telomere dysfunctional bone marrow cells of late generation telomerase knockout mice (G4mTerc(-/-)), increased in blood and various tissues. It can represented human aging and disease. The main aim of this study is to investigate the sensitive direct enzyme-linked immunosorbent assay (ELISA) method to anal...