Dear Sir, the recent issue of Nuclear Medicine Review published an interesting study by Gholamrezanezhad et al. regarding rate dependent left bundle branch block and its effect on myocardial perfusion SPECT [1]. They reported four cases with rate dependent LBBB during exercise stress for myocardial perfusion imaging. Myocardial perfusion SPECT imaging showed no evidence of reversible perfusion ...

OBJECTIVES This study was designed to assess the feasibility and accuracy of positron emission tomography (PET) imaging in infants and children. BACKGROUND Positron emission tomography is employed in adults for the evaluation of myocardial perfusion and the detection of myocardial viability. METHODS Perfusion and metabolism findings on PET in infants and children with suspected coronary abn...

Coronary artery disease (CAD) is the most prevalent and single most common cause of morbidity and mortality [1] with the resulting left ventricular (LV) dysfunction an important complication. The distinction between viable and non-viable myocardium in patients with LV dysfunction is a clinically important issue among possible candidates for myocardial revascularization. Several available non-in...

Background The quest to quantify myocardial perfusion has been largely motivated by the desire to obtain quantitative, observer-independent, and reproducible measures of myocardial perfusion. Spiral pulse sequences have multiple advantages for myocardial perfusion imaging including high acquisition efficiency, high signal to noise (SNR) and robustness to motion. We have developed a spiral pulse...

The concept of ultrafast echocardiographic imaging has been around for decades. However, only recent progress in ultrasound machine hardware and computer technology allowed to apply this echocardiography. High frame rate echocardiography can visualize phenomena that have never captured before. It enables a wide variety potential new applications, including shear wave imaging, speckle tracking, ...

Nitrate-augmented myocardial perfusion imaging has been demonstrated to improve the detection of myocardial viability and accurately predicts recovery of left ventricular (LV) function in patients with severe coronary artery disease and LV dysfunction. Recently, several studies showed the prognostic utility of nitrate imaging in evaluation of event-free survival in ischemic LV dysfunction. Furt...

  Transient ischemic left ventricular dilation (TID) is a marker of severe and extensive coronary artery disease as well as an increased risk of adverse outcomes. The patients with more severe and extensive ischemia, multivessel-type of perfusion abnormality as well as patients with left anterior descending artery (LAD) territory perfusion abnormality have more probab...

Background There is an ongoing debate on the merit of whole-heart 3D CMR perfusion imaging in terms of improving the overall diagnostic accuracy of myocardial perfusion CMR [1]. Whole-heart imaging is technically more challenging [2] and requires a compromise in terms of the spatial resolution [2] and temporal footprint (hence, potentially leading to more instances of artifactual images). The p...

INTRODUCTION The purpose of this study was to investigate the safety of performing a dipyridamole stress test and to explore the incidence of reversible perfusion defects on myocardial perfusion imaging, five to six days after primary percutaneous coronary intervention (PCI). METHODS Forty-one patients underwent myocardial perfusion imaging using a dipyridamole stress test, five to six days a...