BACKGROUND Anthropological studies based on highly polymorphic HLA genes provide useful information for bone marrow donor registry, forensic medicine, disease association studies, as well as designing peptide vaccines against tumors, and infectious or autoimmune diseases. OBJECTIVE This study was designed to investigate the genetic relationship of Iranian Arabs and Jews using HLA-class II gen...

Mutations in plectin, a widely expressed giant cytolinker protein can lead to different diseases mostly with signs of muscular dystrophy (MD) and skin blistering. The only report of plectin-related disease without skin involvement is limb-girdle muscular dystrophy type 2Q (LGMD2Q) phenotype, showing early-onset limb-girdle muscular dystrophy symptoms with progressive manner and no cranial muscl...

BACKGROUND Nitrous oxide (N(2)O) is the oldest anesthetic in routine clinical use and its occupational exposure is under regulation by many countries. As studies are lacking to demonstrate the status of nitrous oxide levels in operating and recovery rooms of Iranian hospitals, we aimed to study its level in teaching hospitals of Tehran University of Medical Sciences. METHODS During a 6-month ...

AIM Preeclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality. There is a genetic component in the development of PE with estimated heritability around 0.47. Several studies have investigated the association between maternal ABO blood groups (OMIM 110300) and risk of PE, with contradictory results have emerged. Considering that there is no study in this filed from Iran...

Background: Coronavirus 2019 is a new infectious disease that has been declared by the World Health Organization as global pandemic. This pandemic may have psychological effects on populations. Objectives: study aimed to investigate quality of sleep and depression in Iranian community during COVID-19 Methods: nationwide cross-sectional web-based was conducted from April 19 May 12, 2020 Iran. Th...

Copyright © 2014, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM); Published by Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. There are many references in ancient Iranian literature on...

OBJECTIVES Iran is considered as one of the high-prevalence areas for β-thalassemia with a rate of about 10% carrier frequency. Molecular diagnosis of the disease is performed both by direct sequencing and indirectly by the use of polymorphic markers present in the beta globin gene cluster. However, to date there is no reliable information on the application of the markers in the Iranian popula...

Iranian traditional architecture is one of the world's architectures par excellence. It was one of the most important architectures in the medieval Islamic world. Iranian architecture has developed over millennia in response to its religion. Many traditional and vernacular buildings in Iran show that the architects had been so clever in harmonizing the Iranian religion and architecture in the p...