نتایج جستجو برای: onychomadesis
تعداد نتایج: 119 فیلتر نتایج به سال:
In recent years, CVA6 has become a new pathogen of Hand, Foot, and Mouth Disease (HFMD), associated with crusted lesions, a rash affecting the arms, trunk, and legs, nail loss. In order to dig out the unclear pathogenesis of CVA6-associated HFMD, we established a reverse genetic system for CVA6 and determined the virulence and the proliferation of the rescued virus. In this study, the CVA6 vira...
The two main layers of human skin are held together by structures at the dermal-epidermal junction (DEJ) called anchoring fibrils (AFs). Without properly functioning AFs, the adherence between the epidermis and dermis is compromised. Clinically, this translates into skin fragility and skin bullae. AFs are composed of type VII collagen (C7) that has a central triple helical domain (TH) flanked b...
Tungiasis is caused by infestation with the sand flea (Tunga penetrans). This ectoparasitosis is endemic in economically depressed communities in South American and African countries. Tungiasis is usually considered an entomologic nuisance and does not receive much attention from healthcare professionals. During a study on tungiasis-related disease in an economically depressed area in Fortaleza...
BACKGROUND Etiology surveillance of Hand Foot and Mouth disease (HFMD) in Beijing showed that Coxsackievirus A6 (CVA6) became the major pathogen of HFMD in 2013 and 2015. In order to understand the epidemiological characteristics and clinical manifestations of CVA6-associated HFMD, a comparison study among CVA6-, EV71- (Enterovirus 71), and CVA16- (Coxsackievirus A16) associated HFMD was perfor...
OBJECTIVE To characterize the atypical cutaneous presentations in the coxsackievirus A6 (CVA6)-associated North American enterovirus outbreak of 2011-2012. METHODS We performed a retrospective case series of pediatric patients who presented with atypical cases of hand, foot, and mouth disease (HFMD) from July 2011 to June 2012 at 7 academic pediatric dermatology centers. Patients were include...
Hallopeau in 1897 1.2 described acrodermatitis continua as characterised by sterile, pustular eruption affecting the skin of the distal phalanges of the fingers and toes, which eventually led to destructive changes of the affected digits. The lesions are usually symmetrical and give rise to persistent erythematous, glazed area of skin. These on occasions developed into generalised pustular psor...
The use of selenium compounds as a cancer treatment predates most conventional treatments currently in use. In spite of this, comparatively little is known regarding the use of selenium as cancer therapy in living systems. Selenium normally acts in concert with a class of enzymes and transporters called Selenoproteins (proteins with selenium in them), many of which are intrinsic anti-oxidant en...
INTRODUCTION Tungiasis is an infestation caused by the penetration in the skin of the gravid female of the flea Tunga penetrans (T. penetrans). The current epidemiological situation of tungiasis in Eastern Africa is poorly known. We present the results of a cross-sectional study on tungiasis which was carried out in Qameyu (Northern Tanzania). METHODOLOGY Sixty-two schoolchildren with suspect...
CASE REPORT A 47-year-old Caucasian man presented to the dermatology department for evaluation of a mass on his left foot. Six years prior, the patient had dropped a sledgehammer on his left great toe causing significant toenail damage, nail loss, and enlarging ulceration despite meticulous wound care. Ten months before presentation, the patient noted rapid growth of the left great toe mass tha...
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