Hand, foot, and mouth disease (HFMD), a common disease caused by enteroviruses (EVs), usually affects children. Clustered and sporadic HFMD cases, followed by onychomadesis (nail shedding), occurred during summer and fall 2008 in Valencia, Spain. Fecal samples from onychomadesis patients, who did or did not have previous HFMD, and from healthy children exposed to onychomadesis patients tested p...

Onychomadesis is a clinical sign of nail plate separation due to transient or permanent arrest of nail matrix activities. Onychomadesis can be considered as a severe form of Beau's line. This condition usually occurs after trauma, causal diseases, or medications, yet it rarely occurs as an idiopathic condition. We report a case of a 38-year-old Thai female who developed recurrence onychomadesis...

In 2015, an outbreak of hand, foot and mouth disease (HFMD) occurred in Romania and many patients presented with onychomadesis following HFMD. We report on five children (3 girls and 2 boys, aged between 3 and 12 years) who were consulted for onychomadesis involving the fingernails and toenails, all of them being diagnosed with HFMD 4-6 weeks ago. We observed no relationship between onychomades...

This paper reported a case of onychomadesis which appeared on the nails after heal of cutaneous lesions of hand-foot-mouth disease (HFMD). There were a few reports describing onychomadesis after HFMD; however, the mechanism is still unclear. The present case was prospectively observed, and onychomadesis was found to develop only on the nails having cutaneous lesions of HFMD. We considered that ...

This report evaluates the June 2008 onychomadesis outbreak in Valencia, Spain. The study sample consisted of 221 onychomadesis cases and 77 nonaffected individuals who lived close to those affected. We collected data on dietary variables, hygiene products, and individual pathological histories. Feces and blood specimens were collected from 44 cases and 24 controls to evaluate exposure to infect...

Valproic acid is an effective, frequently used anticonvulsant drug. Typical adverse effects include weight gain, hair loss, and nausea. Hyperpigmentation, onycholysis, and onychomadesis are nail changes that can be seen after valproic acid use. Changes occur at the distal and proximal portions of the nail bed in onycholysis and onychomadesis, respectively. Onychomadesis is a very rare disease o...

Onychomadesis usually arises from an inflammation of the paronychium or as a result of blisters and hemorrhaging under a nail that has been struck or compressed. No documented interactions between basic fibroblast growth factor (bFGF) and onychomadesis have hitherto been reported. This case report describes a 25-year-old woman with onychomadesis following infection of the ingrown nail of her le...

BACKGROUND Treatment of symmetrical onychomadesis (symmetrical lupoid onychodystrophy) is a challenging task for dermatologists. The acute phase is characterized by sloughing of claw plates and loose claws have to be removed and secondary infections treated. The goal of long-term treatment is to allow claws to re-grow with normal quality and to achieve life-long lack of recurrence. The aim of t...

Vol. 26, No. 6, 2014 777 Received August 7, 2013, Revised December 10, 2013, Accepted for publication December 10, 2013 Corresponding author: Soyun Cho, Department of Dermatology, Seoul National University Boramae Hospital, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 156-707, Korea. Tel: 82-2-870-2385, Fax: 82-2-870-3866, E-mail: [email protected] This is an Open Access article distributed under the t...

Editorials Onychomadesis and hand, foot and mouth disease – is there a connection? Citation style for this article: Haneke E. Onychomadesis and hand, foot and mouth disease – is there a connection?. Onychomadesis is the spontaneous separation of the nail plate from the matrix, a kind of proximal onycholy-sis, and is a common phenomenon due to arrest of nail formation for a certain period. Short...