Homologous recombination DNA repair deficiency is associated with sensitivity to platinum in certain cancer types, including breast, ovarian, pancreatic, and prostate. We aimed characterize the antitumor activity of platinum-based therapies patients (pts) unselected advanced solid tumors for who a gene alteration (DNA-RGA) was identified through tumor molecular screening program (TMSP). All com...

tomato seedlings were inoculated with t. harzianum bi (106 spores/ml) and salicylic acid (5mm) other separately or combined together in the greenhouse environment. the effect of salicylic acid was investigated on growth of antagonistic agent in vitro. for an investigation of the effect of salicylic acid and of antagonist on pathogenecity factor, treatment with t. harzianum bi by drenching soil ...

White Spot Disease (WSD) is well known as a widespread viral disease in shrimps from 1992. Many studies focused on morphological, histopathological and epidemiological characteristic and pathogenecity of the disease but less on the determination of the severity of WSD using the histopathological features in target tissues. A generalized scheme for assigning a numerical qualitative value to sev...

An elevated level of homocysteine, a thiol amino acid, is associated with various complex disorders. The cellular effects of homocysteine and its precursors Sadenosyl homocysteine (SAH) and Sadenosyl methionine (SAM) are however poorly understood. We used Saccharomyces cerevisiae as a model to understand the basis of pathogenicity induced by homocysteine and its precursors. Both homocysteine an...

in order to assay the pathogenicity of the entomopathogenic nematode, heterorhabditis bacteriophora poinar, 1975 on the indigenous population of common earwig, forficula auricularia l., several concentrations including 100, 250, 500, 1000, 1500, 2000 and 3000 (ijs/ml of dw) were used in the laboratory conditions. in this experiment, effects of time (f 1, 91= 4.22, p

pathogenic diversity in didymella rabiei in ilam and kermanshah provinces was assessed with the objective of finding out about the existence of pathotypes. one hundred isolates from different farms of chickpea growing regions in these provinces were collected in 2007. isolates were arranged into ten different groups based upon their sampling regions. one isolate was chosen from anyone of the te...

background and objectives: phospholipase of mycobacterium tuberculosis plays an important role in pathogenesis through breaking up phospholipids and production of diacylglycerol. in this study, we examined the beijing strains of mycobacterium tuberculosis isolated from iranian patients for the genes encoding this enzyme. materials and methods: dna extraction was performed using ctab (cetyltrime...