the nutrients are able to interact with molecular mechanisms and modulate the physiological functions in the body. the nutri­tional genomics focuses on the interaction between bioactive food components and the genome, which includes nutrigenet­ics and nutrigenomics. the influence of nutrients on f genes expression is called nutrigenomics, while the heterogene­ous response of gene variants to nu...

Hereditary hearing loss (HHL) comprises half of the congenital deafness which arises from genetic mutations. Mutations in the TJP2 gene, encoding tight junction protein 2, are one of the gene alterations in HHL resulting in an autosomal dominant nonsyndromic form of the disease. An 11-year-old male patient with clinically approved congenital hearing loss was referred to our laboratory....

This article reports data concerning the Internet-related activities and interest for Ironman Triathlon competition. Google Trends (GT) was used and mined from 2004 onwards. The interest for Ironman Triathlon was found to be cyclic over time. The Triathlon-related Internet activities negatively correlated with the number of finishers per year (Pearson׳s correlation r=-0.690, p-value<0.05), whil...

autosomal dominant polycystic kidney disease (adpkd) is the most common genetic nephropathy, which is characterized by replacement of renal parenchyma with multiple cysts. in iran, the disease prevalence within the chronic hemodialysis patient population is approximately 8-10%. so far, three genetic loci have been identified to be responsible for adpkd. little information is available concernin...

Hip (HD) and Elbow Dysplasia (ED) are two common complex developmental disorders of dogs. In order to decrease their prevalence and severity, the Orthopedic Foundation for Animals (OFA) has a voluntary registry of canine hip and elbow conformation certified by boarded radiologists. However, the voluntarily reports have been severely biased against exposing dogs with problems, especially at begi...

background and aims: charcot marie tooth disease (cmt) is the most prevalent hereditary neuropathy and its frequency is 1 in 2500. cmt is a heterogeneous disease and has different clinical symptoms. the prevalence of cmt and involved genes differ in different countries. cmt patients experience considerable sleep problems and a higher risk of decreased quality of life. in this work it was aimed ...